Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 5741
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50059860(((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...)
Affinity DataKi:  4.70nMAssay Description:Assay using farnesyl-ras-CVLS as the protein acceptor substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50059860(((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...)
Affinity DataKi:  5.20nMAssay Description:FPTase activity was assayed in the biosynthetically forward direction at 30C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)
Affinity DataKi:  830nMAssay Description:FPTase activity was assayed in the biosynthetically forward direction at 30C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)
Affinity DataKi:  1.30E+3nMAssay Description:Assay using farnesyl-ras-CVLS as the protein acceptor substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed