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Found 22 Enz. Inhib. hit(s) with all data for entry = 50037648
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)
Affinity DataIC50:  280nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175792((R)-1-[4,4-bis(3-(phenoxymethyl)-2-thienyl)-3-bute...)
Affinity DataIC50:  340nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175796(1-(4,4-bis(3-(phenoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50:  650nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175799((R)-1-(4,4-bis(3-(cyclohexyloxymethyl)thiophen-2-y...)
Affinity DataIC50:  680nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175783((R)-1-(4,4-bis(3-(benzyloxymethyl)thiophen-2-yl)bu...)
Affinity DataIC50:  840nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175790(1-(4,4-bis(3-(cyclohexyloxymethyl)thiophen-2-yl)bu...)
Affinity DataIC50:  940nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175784(1-(4,4-bis(3-(cyclohexyloxymethyl)thiophen-2-yl)bu...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175791(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)piperi...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175786(1-(4,4-bis(3-(phenoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175788((R)-1-(4,4-bis(3-(methoxymethyl)thiophen-2-yl)but-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175793(1-(4,4-bis(3-(benzyloxymethyl)thiophen-2-yl)but-3-...)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175800((R)-1-(4,4-bis(3-(isopropoxymethyl)thiophen-2-yl)b...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175795(1-(4,4-bis(3-(methoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175785(1-(4,4-bis(3-(benzyloxymethyl)thiophen-2-yl)but-3-...)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175802((R)-1-(4,4-bis(3-((naphthalen-1-yloxy)methyl)thiop...)
Affinity DataIC50:  6.63E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50020883((R)-Piperidine-3-carboxylic acid | (R)-nipecotic a...)
Affinity DataIC50:  8.15E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175794(1-(4,4-bis(3-((naphthalen-1-yloxy)methyl)thiophen-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175787(1-(4,4-bis(3-(isopropoxymethyl)thiophen-2-yl)but-3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175797(1-(4,4-bis(3-(isopropoxymethyl)thiophen-2-yl)but-3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175789(1-(4,4-bis(3-((naphthalen-1-yloxy)methyl)thiophen-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175801(1-(4,4-bis(3-(methoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175798(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)piperi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed