Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 1984
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15805(Macrocyclic BACE inhibitor 7 | tert-butyl N-[(2S)-...)
Affinity DataIC50:  65nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15799(CHEMBL81671 | Macrocyclic BACE inhibitor 1 | tert-...)
Affinity DataIC50:  82nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15804(Macrocyclic BACE inhibitor 6 | tert-butyl N-[(2S)-...)
Affinity DataIC50:  260nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15801(Macrocyclic BACE inhibitor 3 | tert-butyl N-[(3S,6...)
Affinity DataIC50:  285nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15803((2R,4S)-4-[(2S,5S,12S)-12-amino-2-methyl-3,13-diox...)
Affinity DataIC50:  2.40E+3nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15802(Macrocyclic BACE inhibitor 4 | tert-butyl N-[(3S,6...)
Affinity DataIC50:  4.93E+3nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15800(Macrocyclic BACE inhibitor 2 | tert-butyl N-[(3S,6...)
Affinity DataIC50:  9.70E+3nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed