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Found 14 Enz. Inhib. hit(s) with all data for entry = 50017193
LigandPNGBDBM50178874(7-(2-hydroxy-3-(naphthalen-2-yloxy)propyl)-8-merca...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178873(4-((3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)p...)
Affinity DataIC50:  700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178877(2-(6-amino-3,5-dicyano-4-phenylpyridin-2-ylthio)-N...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50178873(4-((3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)p...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178871(4-(5-((3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50178876(5-(2-(2-methoxyphenylamino)thiazol-4-yl)-4-methylt...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50178872(2-(5-methyl-thiophen-2-yl)-quinoline-4-carboxylic ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50178871(4-(5-((3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178876(5-(2-(2-methoxyphenylamino)thiazol-4-yl)-4-methylt...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178875(4-[5-(4-Oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50178875(4-[5-(4-Oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50178877(2-(6-amino-3,5-dicyano-4-phenylpyridin-2-ylthio)-N...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178872(2-(5-methyl-thiophen-2-yl)-quinoline-4-carboxylic ...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178874(7-(2-hydroxy-3-(naphthalen-2-yloxy)propyl)-8-merca...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed