Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50017241
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  5nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataKi:  9nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataKi:  10nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  13nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataKi:  23nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataKi:  24nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  30nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataKi:  37nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataKi:  71nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataKi:  76nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  104nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataKi:  214nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataKi:  214nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  220nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataKi:  382nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  468nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataKi:  1.63E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.73E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataKi:  2.28E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  2.41E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  3.99E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  4.52E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  6.20E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataKi:  8.56E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataKi:  1.23E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataKi:  1.80E+4nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  2.23E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataKi:  2.34E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataKi:  2.47E+4nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataKi:  5.55E+4nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  22nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataEC50:  10nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataEC50:  142nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataEC50:  20nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataEC50:  38nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  44nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataEC50:  193nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataEC50:  8nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataEC50:  10nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  160nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed