Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 1060
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8525(4-{[(1S,2R,4S,5R)-2,4-bis(carbamimidamidomethyl)-5...)
Affinity DataKi:  65nM ΔG°:  -40.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM19((2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3...)
Affinity DataKi:  500nM ΔG°:  -36.0kJ/moleT: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8524((1R,2S,4R,5S)-2,4-bis(carbamimidamidomethyl)-5-(2,...)
Affinity DataKi:  500nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8517(4-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  600nM ΔG°:  -35.2kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8519(2-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  4.10E+3nM ΔG°:  -30.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8518(6-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  6.60E+3nM ΔG°:  -29.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8521(4-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  1.07E+4nM ΔG°:  -28.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8515(4-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  1.49E+4nM ΔG°:  -27.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8523((1S,2R,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-hyd...)
Affinity DataKi:  2.48E+4nM ΔG°:  -26.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8516(2-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  3.06E+4nM ΔG°:  -25.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8520(4-[(1S,2S,4S,5R)-2,4-bis(carbamimidamidomethyl)-5-...)
Affinity DataKi:  3.14E+4nM ΔG°:  -25.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataKi:  4.29E+4nM ΔG°:  -24.9kJ/moleT: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8522(3-{[(1S,2S,4R,5S)-2-(2-amino-1H-1,3-benzodiazol-6-...)
Affinity DataKi:  1.54E+5nM ΔG°:  -21.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed