Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 1056
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8458(5-[(5-phenylthiophen-2-yl)methylidene]-2-sulfanyli...)
Affinity DataIC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8456(5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-...)
Affinity DataIC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8457(5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylidene}-...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8459(2-[(5Z)-4-oxo-2-sulfanylidene-5-{[5-(thiophen-2-yl...)
Affinity DataIC50:  2.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8464(5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl]methyli...)
Affinity DataIC50:  3.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8460(5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}-2-su...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8451(2-[(5Z)-5-{[5-(4-bromophenyl)-1,3-thiazol-2-yl]met...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8450(2-[(5Z)-5-{[5-(3,4-dimethoxyphenyl)-1,3-thiazol-2-...)
Affinity DataIC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8463(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  5.60E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8452(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  5.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8449(2-[(5Z)-5-{[5-(4-chlorophenyl)-1,3-thiazol-2-yl]me...)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8461(2-[(5Z)-4-oxo-5-[(5-phenylfuran-2-yl)methylidene]-...)
Affinity DataIC50:  1.66E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8462(2-[(5Z)-5-{[5-(4-fluorophenyl)-1,3-thiazol-2-yl]me...)
Affinity DataIC50:  2.24E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8454((5E)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]fur...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8455(Creatinine acetic acid analogue 20 | [(5E)-5-{[5-(...)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8453((5E)-5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}...)
Affinity DataIC50:  2.00E+5nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed