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Found 161 Enz. Inhib. hit(s) with all data for entry = 50037642
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  1.69nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50370693(CHEMBL1202298)
Affinity DataKi:  2.32nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  3.09nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  6.93nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  8.47nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  10.7nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  11.2nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  11.3nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  14.7nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  16.4nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  17.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50370693(CHEMBL1202298)
Affinity DataKi:  20.7nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  22.3nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  33.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  33.7nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  40.4nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  47.5nMAssay Description:Inhibition of binding to human D3 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  52.5nMAssay Description:Inhibition of binding to human D3 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  56.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  61nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50370693(CHEMBL1202298)
Affinity DataKi:  65.7nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  79.1nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  82.6nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  92nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180931(3-methyl-6-phenyl-1,2,3,4,5,6,7,8-octahydroazonino...)
Affinity DataKi:  112nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180925(11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(1...)
Affinity DataKi:  134nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50370693(CHEMBL1202298)
Affinity DataKi:  165nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  170nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  198nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  207nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  253nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  264nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  299nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  337nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50370693(CHEMBL1202298)
Affinity DataKi:  341nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  361nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  379nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180917(2,3-dimethoxy-7-methyl-5,6,7,8,9,14-hexahydrodiben...)
Affinity DataKi:  509nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  712nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180931(3-methyl-6-phenyl-1,2,3,4,5,6,7,8-octahydroazonino...)
Affinity DataKi:  742nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180904(7-cyclopropylmethyl-6,7,8,9,14,15-hexahydro-5H-ben...)
Affinity DataKi:  767nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180904(7-cyclopropylmethyl-6,7,8,9,14,15-hexahydro-5H-ben...)
Affinity DataKi:  893nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180931(3-methyl-6-phenyl-1,2,3,4,5,6,7,8-octahydroazonino...)
Affinity DataKi:  943nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50370693(CHEMBL1202298)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180912(3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3...)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180917(2,3-dimethoxy-7-methyl-5,6,7,8,9,14-hexahydrodiben...)
Affinity DataKi:  2.51E+3nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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