Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50017454
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182352(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(difluorome...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182338(2-(5-(4-(furan-2-yl)-3-methylphenyl)-3-(trifluorom...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182347(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(trifluorom...)
Affinity DataIC50:  12nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182339(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)
Affinity DataIC50:  13nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182353(2-(3-(difluoromethyl)-5-(3-methyl-4-(thiazol-4-yl)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182332(2-(5-(4-(furan-2-yl)phenyl)-3-(trifluoromethyl)-1H...)
Affinity DataIC50:  20nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182345(2-(5-(3-methyl-4-(oxazol-4-yl)phenyl)-3-(trifluoro...)
Affinity DataIC50:  30nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182335(2-(5-(3-fluoro-4-(furan-2-yl)phenyl)-3-(trifluorom...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182351(2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182334(2-(3-(difluoromethyl)-5-(3-fluoro-4-(furan-2-yl)ph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182346(2-(5-(3-methyl-4-(oxazol-2-yl)phenyl)-3-(trifluoro...)
Affinity DataIC50:  65nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182333(2-(5-(3-methyl-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182340(5-(1-(5-(methylsulfonyl)pyridin-2-yl)-3-(trifluoro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182343(2-(3-(difluoromethyl)-5-(4-(furan-2-yl)phenyl)-1H-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182342(5-(methylsulfonyl)-2-(5-(4-(thiazol-4-yl)phenyl)-3...)
Affinity DataIC50:  160nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182349(5-(methylsulfonyl)-2-(5-(4-(thiazol-5-yl)phenyl)-3...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182336(5-(methylsulfonyl)-2-(5-(4-(thiazol-2-yl)phenyl)-3...)
Affinity DataIC50:  210nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182337(2-(5-(2-fluoro-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50:  290nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182350(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)
Affinity DataIC50:  410nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182348(5-(methylsulfonyl)-2-(5-(4-(5-methylthiazol-4-yl)p...)
Affinity DataIC50: >500nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182341(CHEMBL383470 | methyl 2-(furan-2-yl)-5-(1-(5-(meth...)
Affinity DataIC50: >500nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182344(5-(methylsulfonyl)-2-(5-(3-(thiazol-4-yl)phenyl)-3...)
Affinity DataIC50: >500nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182339(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182350(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182349(5-(methylsulfonyl)-2-(5-(4-(thiazol-5-yl)phenyl)-3...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182338(2-(5-(4-(furan-2-yl)-3-methylphenyl)-3-(trifluorom...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182353(2-(3-(difluoromethyl)-5-(3-methyl-4-(thiazol-4-yl)...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182334(2-(3-(difluoromethyl)-5-(3-fluoro-4-(furan-2-yl)ph...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182352(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(difluorome...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182346(2-(5-(3-methyl-4-(oxazol-2-yl)phenyl)-3-(trifluoro...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182343(2-(3-(difluoromethyl)-5-(4-(furan-2-yl)phenyl)-1H-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182345(2-(5-(3-methyl-4-(oxazol-4-yl)phenyl)-3-(trifluoro...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182333(2-(5-(3-methyl-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182351(2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182332(2-(5-(4-(furan-2-yl)phenyl)-3-(trifluoromethyl)-1H...)
Affinity DataIC50:  1.82E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182337(2-(5-(2-fluoro-4-(thiazol-4-yl)phenyl)-3-(trifluor...)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182340(5-(1-(5-(methylsulfonyl)pyridin-2-yl)-3-(trifluoro...)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182335(2-(5-(3-fluoro-4-(furan-2-yl)phenyl)-3-(trifluorom...)
Affinity DataIC50:  2.79E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182336(5-(methylsulfonyl)-2-(5-(4-(thiazol-2-yl)phenyl)-3...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182347(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(trifluorom...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182342(5-(methylsulfonyl)-2-(5-(4-(thiazol-4-yl)phenyl)-3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed