Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50017486
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157734(2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyr...)
Affinity DataIC50:  570nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182775(3-allyl-5,8-dichloro-1,2,3,4-tetrahydrocyclopenta[...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182777(3-butyl-8-cyano-7-fluoro-5-methyl-1,2,3,4-tetrahyd...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182768(8-cyano-7-fluoro-5-methyl-3-propyl-1,2,3,4-tetrahy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182788(3-butyl-5,8-dichloro-1,2,3,4-tetrahydrocyclopenta[...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182786(2-(5-cyano-8-fluoro-1-propyl-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182765(2-(5-cyano-8-methyl-1-propyl-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182769(2-(5,8-dicyano-1-propyl-2,3,4,9-tetrahydro-1H-carb...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182785(5,8-dichloro-1-propyl-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182789(3-butyl-8-cyano-5-methyl-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182783(8-cyano-5-methyl-3-propyl-1,2,3,4-tetrahydrocyclop...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182774(3-butyl-8-cyano-5-fluoro-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182776(8-chloro-1-propyl-5-(trifluoromethyl)-2,3,4,9-tetr...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182773(3-allyl-8-cyano-7-fluoro-5-methyl-1,2,3,4-tetrahyd...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182778(8-cyano-5-fluoro-3-propyl-1,2,3,4-tetrahydrocyclop...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182781(5-cyano-8-fluoro-1-propyl-2,3,4,9-tetrahydro-1H-ca...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182780(3-allyl-8-cyano-5-methyl-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182767(3-allyl-8-cyano-5-fluoro-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182770(5-cyano-8-methyl-1-propyl-2,3,4,9-tetrahydro-1H-ca...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182771(5,8-dichloro-3-propyl-1,2,3,4-tetrahydrocyclopenta...)
Affinity DataIC50:  2.70E+4nMAssay Description:Antiviral activity against Hepatitis C virus replicon in Huh7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182771(5,8-dichloro-3-propyl-1,2,3,4-tetrahydrocyclopenta...)
Affinity DataIC50:  2.70E+4nMAssay Description:Antiviral activity against Hepatitis C virus replicon in Huh7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182779(2-(5,7-difluoro-1-propyl-2,3,4,9-tetrahydro-1H-car...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182790(2-(6-chloro-1-propyl-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182772(2-(8-carbamoyl-5-cyano-1-propyl-2,3,4,9-tetrahydro...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182784(2-(1-propyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)ac...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182787(2-(5,8-difluoro-1-propyl-2,3,4,9-tetrahydro-1H-car...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182782(2-(6-bromo-8-chloro-1-propyl-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50182766(2-(7,8-difluoro-1-propyl-2,3,4,9-tetrahydro-1H-car...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed