Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50037674
TargetCysteine protease(Leishmania donovani)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  15nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  75nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183375(CHEMBL381093 | N2,N7-bis(furan-2-ylmethyl)-9H-fluo...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183403(CHEMBL203801 | N'-(1-(2-(m-toluidino)-2-oxoethyl)-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183382(5-Isoxazol-3-yl-thiophene-2-sulfonic acid (5-dimet...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183386(2-(2-(4-chlorophenylsulfonyl)ethylthio)-N-(4-(prop...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183385(CHEMBL203823 | N-(2-(furan-2-ylmethylthio)ethyl)-2...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183392(4-(5-(5-(morpholinosulfonyl)thiophen-2-yl)thiophen...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183376((N1',N6')-N1',N6'-bis(1-methyl-2-oxoindolin-3-ylid...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183377(CHEMBL383231 | methyl 3-[(3-{[2-(methoxycarbonyl)t...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183404(CHEMBL204035 | N'-((2-chloro-6-fluorobenzyloxyamin...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183375(CHEMBL381093 | N2,N7-bis(furan-2-ylmethyl)-9H-fluo...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183405(4,6-dimethyl-N,N-bis(2-(phenylsulfonyl)ethyl)-1,3,...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183397(CHEMBL440764 | ethyl 2-(2-(furan-2-ylmethylamino)-...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183402(CHEMBL205056 | methyl 2-(2-(4-(4-chlorophenylsulfo...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183389(CHEMBL204491 | N-benzyl-3-(2-benzylcarbamoyl-ethyl...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183389(CHEMBL204491 | N-benzyl-3-(2-benzylcarbamoyl-ethyl...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183408(1-((1-(phenylsulfonyl)piperidin-4-yl)methyl)-3-tos...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Leishmania donovani)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183399((S)-3-benzyloxy-2-benzyloxycarbonylamino-propionic...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Leishmania donovani)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183384(2-(4-chlorophenylsulfonyl)-N-(2-(phenylsulfonyl)et...)
Affinity DataIC50:  2.49E+4nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183397(CHEMBL440764 | ethyl 2-(2-(furan-2-ylmethylamino)-...)
Affinity DataIC50:  3.12E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Leishmania donovani)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183381((S)-benzyl 2-(2-(benzyloxycarbonylamino)acetamido)...)
Affinity DataIC50:  3.14E+4nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183408(1-((1-(phenylsulfonyl)piperidin-4-yl)methyl)-3-tos...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183392(4-(5-(5-(morpholinosulfonyl)thiophen-2-yl)thiophen...)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183404(CHEMBL204035 | N'-((2-chloro-6-fluorobenzyloxyamin...)
Affinity DataIC50:  3.85E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Leishmania donovani)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183401(2-(benzo[d]oxazol-2-ylthio)-N-(2-(furan-2-ylmethyl...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183390(5-((4-chlorobenzylsulfonyl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  4.78E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183402(CHEMBL205056 | methyl 2-(2-(4-(4-chlorophenylsulfo...)
Affinity DataIC50:  4.92E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183376((N1',N6')-N1',N6'-bis(1-methyl-2-oxoindolin-3-ylid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183377(CHEMBL383231 | methyl 3-[(3-{[2-(methoxycarbonyl)t...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183396(2-[(4-fluorobenzyl)sulfonyl]-N'-[(thien-2-ylcarbon...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183403(CHEMBL203801 | N'-(1-(2-(m-toluidino)-2-oxoethyl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183382(5-Isoxazol-3-yl-thiophene-2-sulfonic acid (5-dimet...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183405(4,6-dimethyl-N,N-bis(2-(phenylsulfonyl)ethyl)-1,3,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183371(CHEMBL204973 | N'-benzylidene-2-(3-((4-methylthiaz...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183398(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(4-(fura...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183386(2-(2-(4-chlorophenylsulfonyl)ethylthio)-N-(4-(prop...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183396(2-[(4-fluorobenzyl)sulfonyl]-N'-[(thien-2-ylcarbon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183385(CHEMBL203823 | N-(2-(furan-2-ylmethylthio)ethyl)-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183398(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(4-(fura...)
Affinity DataIC50:  5.23E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183371(CHEMBL204973 | N'-benzylidene-2-(3-((4-methylthiaz...)
Affinity DataIC50:  5.43E+4nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50183390(5-((4-chlorobenzylsulfonyl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  5.66E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed