Compile Data Set for Download or QSAR
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Found 30 Enz. Inhib. hit(s) with all data for entry = 50017613
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  62nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184590((3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  108nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(CHEMBL208936 | rac-1-(4-(trifluoromethyl)pyrimidin...)
Affinity DataEC50:  320nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  25nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184588((3aS,4S,6aR)-4-(3-(trifluoromethyl)phenyl)-octahyd...)
Affinity DataEC50:  420nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184589((3aS,6aS)-1-(4-(2,5-dichlorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184590((3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  319nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184591((3aS,6aS)-1-(4-(2,5-difluorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(CHEMBL208936 | rac-1-(4-(trifluoromethyl)pyrimidin...)
Affinity DataEC50:  220nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184588((3aS,4S,6aR)-4-(3-(trifluoromethyl)phenyl)-octahyd...)
Affinity DataEC50:  1.08E+3nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184588((3aS,4S,6aR)-4-(3-(trifluoromethyl)phenyl)-octahyd...)
Affinity DataEC50:  187nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184592((3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydrop...)
Affinity DataEC50:  65nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(CHEMBL208936 | rac-1-(4-(trifluoromethyl)pyrimidin...)
Affinity DataEC50:  180nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  48nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184590((3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  1.12E+3nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184592((3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydrop...)
Affinity DataEC50:  103nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184585((3aS,6aS)-1-(3-chlorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  416nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184595((3aR,6aR)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  519nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184594((3aS,6aS)-5-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50: >2.00E+4nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  151nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  116nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  23nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184592((3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydrop...)
Affinity DataEC50:  168nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  57nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184585((3aS,6aS)-1-(3-chlorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  503nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184597((3aS,6aS)-5-(4-(2,5-dichlorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >2.00E+4nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  40nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  22nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184593((3aS,6aS)-5-(4-(2,5-difluorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >2.00E+4nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184585((3aS,6aS)-1-(3-chlorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  59nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed