Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50017624
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184690(CHEMBL210887 | N-(1-(3-hydroxypropyl)-1H-benzo[d]i...)
Affinity DataIC50:  150nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184706(CHEMBL379787 | N-(1-(2-morpholinoethyl)-1H-benzo[d...)
Affinity DataIC50:  200nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184706(CHEMBL379787 | N-(1-(2-morpholinoethyl)-1H-benzo[d...)
Affinity DataIC50:  300nMAssay Description:Inhibition of IRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184695(CHEMBL210194 | ethyl 2-(2-(3-nitrobenzamido)-1H-be...)
Affinity DataIC50:  400nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184693(CHEMBL379985 | N-(1-(2-hydroxyethyl)-1H-benzo[d]im...)
Affinity DataIC50:  400nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184705(3-nitro-N-(1-((tetrahydrofuran-2-yl)methyl)-1H-ben...)
Affinity DataIC50:  500nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184702(3-nitro-N-(1-(2-oxo-tetrahydrofuran-3-yl)-1H-benzo...)
Affinity DataIC50:  550nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184695(CHEMBL210194 | ethyl 2-(2-(3-nitrobenzamido)-1H-be...)
Affinity DataIC50:  750nMAssay Description:Inhibition of IRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184699(CHEMBL377259 | N-(5-methyl-1H-benzo[d]imidazol-2-y...)
Affinity DataIC50:  800nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184707(CHEMBL209202 | N-(1-isopropyl-1H-benzo[d]imidazol-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184696(CHEMBL210354 | N-(1-(2-methoxyethyl)-1H-benzo[d]im...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184689(CHEMBL210774 | N-(1-allyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184692(CHEMBL208709 | ethyl 3-(2-(3-nitrobenzamido)-1H-be...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184714(CHEMBL206991 | N-(5-methoxy-1H-benzo[d]imidazol-2-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184704(CHEMBL208166 | N-(1-(2-cyclobutylethyl)-1H-benzo[d...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184718(CHEMBL210366 | N-(1-(2-ethoxyethyl)-1H-benzo[d]imi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184710(CHEMBL209716 | N-(1-butyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184709(CHEMBL210822 | N-(1-ethyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184694(CHEMBL209075 | N-(1-butyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184715(CHEMBL378693 | N-(1-(2-(diethylamino)ethyl)-1H-ben...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184722(3-(2-(3-nitrobenzamido)-1H-benzo[d]imidazol-1-yl)p...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184697(3-nitro-N-(5-(propylsulfonyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184713(CHEMBL377801 | N-(1-(3-(dimethylamino)propyl)-1H-b...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184701(CHEMBL210658 | N-(1H-benzo[d]imidazol-2-yl)-3-nitr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184719(CHEMBL208116 | N-(5-fluoro-1H-benzo[d]imidazol-2-y...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184721(CHEMBL210682 | N-(5-chloro-1H-benzo[d]imidazol-2-y...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184698(CHEMBL380097 | N-(1-butyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184708(CHEMBL209118 | N-(1H-benzo[d]imidazol-2-yl)-4-fluo...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184712(CHEMBL210821 | N-(5,6-dimethyl-1H-benzo[d]imidazol...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184716(CHEMBL209715 | N-(1H-benzo[d]imidazol-2-yl)-4-meth...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184703(CHEMBL426133 | N-(1H-benzo[d]imidazol-2-yl)-3-cyan...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184717(3-nitro-N-(1-pentyl-1H-benzo[d]imidazol-2-yl)benza...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184700(CHEMBL208561 | methyl 2-(3-nitrobenzamido)-1H-benz...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184724(CHEMBL208743 | N-methyl-3-nitro-N-(1-(2-oxo-tetrah...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184723(CHEMBL210714 | N-allyl-N-(1-allyl-1H-benzo[d]imida...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184720(CHEMBL208667 | N-(5,6-difluoro-1H-benzo[d]imidazol...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184711(CHEMBL377654 | N-(1-butyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50184691(CHEMBL380009 | N-(3H-imidazo[4,5-c]pyridin-2-yl)-3...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed