Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 1898
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  13nM ΔG°:  -44.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14880(1-(2,4-dimethoxyphenyl)-3-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  28nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14872(1-(2,6-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  33nM ΔG°:  -42.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14877(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  47nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14869(1-(2-fluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  57nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14876(1-(2-chlorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  57nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14883(4-[({[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-y...)
Affinity DataKi:  58nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14881(1-(3-acetylphenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  60nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14868(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  61.5nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14896(1-benzyl-1-hydroxy-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  72nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14879(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  88nM ΔG°:  -39.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14873(1-(2,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  100nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14878(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  100nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14871(1-(4-fluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  110nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14870(1-(3-fluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  130nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14885(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  130nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14887(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  155nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14884(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  160nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14882(1-(4-acetylphenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[...)
Affinity DataKi:  190nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14892(3-hydroxy-N-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataKi:  220nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14866(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  270nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14874(1-(3,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  330nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14865(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  335nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14867(1-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  350nM ΔG°:  -36.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14893(3-hydroxy-N-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataKi:  610nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  800nM ΔG°:  -34.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14875(1-(3,5-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  830nM ΔG°:  -34.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14894(2-hydroxy-N-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataKi:  850nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14890(5-azaindole analog 28 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  2.00E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  2.70E+3nM ΔG°:  -31.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14886(3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}...)
Affinity DataKi:  2.70E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14895(5-azaindole analog 33 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  2.80E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  3.60E+3nM ΔG°:  -30.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14891(2-(2,6-difluorophenyl)-N-{[3-(2-hydroxy-3-{1H-pyrr...)
Affinity DataKi:  9.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14888(5-azaindole analog 26 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  1.70E+4nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  4.65E+4nM ΔG°:  -24.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  7.15E+4nM ΔG°:  -23.4kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  9.00E+4nM ΔG°:  -22.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  1.25E+5nM ΔG°:  -22.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14889(5-azaindole analog 27 | N-{[3-(2-hydroxy-3-{1H-pyr...)
Affinity DataKi:  1.30E+5nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed