Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 2808
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24923(5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-b...)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24922(5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[...)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24899(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylca...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24901(3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24898(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(methylcar...)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24919(3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24900(3-{[1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylc...)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24918(5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-ind...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24903(3-{[1-(4-chlorophenyl)-2-methylpropyl]sulfanyl}-5-...)
Affinity DataIC50:  16nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24910(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-3-...)
Affinity DataIC50:  19nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24914(3-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50:  28nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24911(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-(pyridin-3...)
Affinity DataIC50:  29nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24909(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-2-...)
Affinity DataIC50:  33nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24904(3-{[1-(4-chlorophenyl)butyl]sulfanyl}-5-[(methylca...)
Affinity DataIC50:  35nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24913(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50:  45nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24915(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-...)
Affinity DataIC50:  47nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24902(3-{[(1S)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)
Affinity DataIC50:  52nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24917(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-oxo-1,6...)
Affinity DataIC50:  84nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24924(5-(carbamoylamino)-3-[(5S)-6,7,8,9-tetrahydro-5H-b...)
Affinity DataIC50:  91nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24920(5-(carbamoylamino)-3-(1,2,3,4-tetrahydronaphthalen...)
Affinity DataIC50:  105nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24905(3-{[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]sulfan...)
Affinity DataIC50:  110nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24921(5-[(methylcarbamoyl)amino]-3-(1,2,3,4-tetrahydrona...)
Affinity DataIC50:  111nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24916(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-methoxy...)
Affinity DataIC50:  179nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24912(3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamin...)
Affinity DataIC50:  610nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24906(3-{[(4-chlorophenyl)(phenyl)methyl]sulfanyl}-5-[(m...)
Affinity DataIC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24908(5-amino-3-{[(4-chlorophenyl)methyl]sulfanyl}-1,2-t...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24907(1-(3-{[(4-chlorophenyl)methyl]sulfanyl}-4-cyano-1,...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed