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Found 28 Enz. Inhib. hit(s) with all data for entry = 1399
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11264(N-(3,5-dichlorophenyl)-2-{[4-(2-phenyl-1,3-thiazol...)
Affinity DataIC50:  3.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11265(N-(4-chlorophenyl)-2-[(4-{5-[1-methyl-5-(trifluoro...)
Affinity DataIC50:  1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11266(N-(4-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3...)
Affinity DataIC50:  1.10E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11267(N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3...)
Affinity DataIC50:  1.20E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11268(N-(4-chlorophenyl)-2-({4-[2-(2-methyl-1,3-thiazol-...)
Affinity DataIC50:  1.40E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11269(N-(4-chlorophenyl)-2-{[4-(3-phenyl-1,2-oxazol-5-yl...)
Affinity DataIC50:  1.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11271(N-(4-chlorophenyl)-2-({4-[3-(2-chlorophenyl)-1,2-o...)
Affinity DataIC50:  1.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11270(2-({4-[3-(2,4-dichlorophenyl)-1,2-oxazol-5-yl]pyri...)
Affinity DataIC50:  1.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11272(N-(4-chlorophenyl)-2-[(4-hydroxy-6-propylpyrimidin...)
Affinity DataIC50:  3.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11274(N-[4-(propan-2-yl)phenyl]-2-{[4-(thiophen-2-yl)pyr...)
Affinity DataIC50:  4.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11273(2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydrop...)
Affinity DataIC50:  4.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11275(N-(3,4-dimethoxyphenyl)-2-[(4-hydroxy-6-phenylpyri...)
Affinity DataIC50:  4.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11276(2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydrop...)
Affinity DataIC50:  6.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11277(2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydrop...)
Affinity DataIC50:  6.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11278(N-(5-chloro-2-phenoxyphenyl)-2-[(4-methyl-6-oxo-1,...)
Affinity DataIC50:  1.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11279(N-[4-(4-chlorophenoxy)phenyl]-2-[(4-hydroxy-6-meth...)
Affinity DataIC50:  2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11280(2-({4-[2-(2-chlorophenoxymethyl)-1,3-thiazol-4-yl]...)
Affinity DataIC50:  2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11281(2-{[4-(dimethoxymethyl)-6-hydroxypyrimidin-2-yl]su...)
Affinity DataIC50:  2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11282(N-(4-butyl-2-methylphenyl)-2-[(5-cyano-4-cyclohexy...)
Affinity DataIC50:  2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11283(2-[(5-cyano-6-oxo-4-phenyl-1,6-dihydropyrimidin-2-...)
Affinity DataIC50:  2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11284(ethyl 4-amino-2-({[(4-nitrophenyl)carbamoyl]methyl...)
Affinity DataIC50:  2.50E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11285(3-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-1-(4-etho...)
Affinity DataIC50:  3.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11286(2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydrop...)
Affinity DataIC50:  3.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11287(N-(4-chlorophenyl)-2-[(5-cyano-6-oxo-4-phenyl-1,6-...)
Affinity DataIC50:  3.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11288(N-(4-tert-butylphenyl)-2-[(5-cyano-4-cyclohexyl-6-...)
Affinity DataIC50:  3.50E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11289(2-{[4-(4-methoxyphenyl)pyrimidin-2-yl]sulfanyl}-N-...)
Affinity DataIC50:  4.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11290(N-(4-chloro-2-fluorophenyl)-2-{[4-methyl-6-(triflu...)
Affinity DataIC50:  5.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11291(2-[(4-hydroxy-5,6-dimethylpyrimidin-2-yl)sulfanyl]...)
Affinity DataIC50: >1.00E+6nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed