Compile Data Set for Download or QSAR
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Found 42 Enz. Inhib. hit(s) with all data for entry = 50037729
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189627(CHEMBL212460 | N-{3-[4-(4-isopropoxyphenoxy)phenyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189631(CHEMBL376983 | N-(4-(2-(4-phenoxyphenoxy)thiazol-5...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189620(CHEMBL208680 | N-{3-[2-(6-isopropoxy-pyridin-3-ylo...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189630(CHEMBL377212 | N-(4-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189622(CHEMBL208672 | {1-methyl-3-[2-(4-phenoxy-phenoxy)-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189627(CHEMBL212460 | N-{3-[4-(4-isopropoxyphenoxy)phenyl...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189615(1-(4-(2-(4-isopropoxyphenoxy)thiazol-5-yl)but-3-yn...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189628((S)-(-)-{3-[2-(4-isopropoxy-phenoxy)-thiazol-4-yl]...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against rat ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189624(CHEMBL377535 | N-(4-(2-(4-(isopropylthio)phenoxy)t...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  61nMAssay Description:Inhibitory activity against rat ACC2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189623(CHEMBL208880 | N-{3-[2-(4-isopropoxy-phenylsulfany...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189633(1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)b...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189621(CHEMBL426325 | methyl 4-(2-(4-isopropoxyphenoxy)th...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189629(CHEMBL208555 | N-(4-(2-(4-(isopropylamino)phenoxy)...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189631(CHEMBL376983 | N-(4-(2-(4-phenoxyphenoxy)thiazol-5...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189624(CHEMBL377535 | N-(4-(2-(4-(isopropylthio)phenoxy)t...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189620(CHEMBL208680 | N-{3-[2-(6-isopropoxy-pyridin-3-ylo...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189634(4-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-but-3-yn-2-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189626(CHEMBL209279 | N-(1-cyclopropyl-3-(2-(4-isopropoxy...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189633(1-hydroxy-1-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)b...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189632(CHEMBL408331 | N-{3-[2-(4-isopropyl-phenoxy)-thiaz...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189625((R)-(+)-{3-[2-(4-isopropoxy-phenoxy)-thiazol-5-yl]...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189616(CHEMBL210384 | N-(3-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189619(1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-pr...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189629(CHEMBL208555 | N-(4-(2-(4-(isopropylamino)phenoxy)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189634(4-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-but-3-yn-2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189615(1-(4-(2-(4-isopropoxyphenoxy)thiazol-5-yl)but-3-yn...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189616(CHEMBL210384 | N-(3-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189618(CHEMBL554385 | N-{3-[2-(4-isopropoxy-phenoxy)-thia...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189618(CHEMBL554385 | N-{3-[2-(4-isopropoxy-phenoxy)-thia...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189632(CHEMBL408331 | N-{3-[2-(4-isopropyl-phenoxy)-thiaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189621(CHEMBL426325 | methyl 4-(2-(4-isopropoxyphenoxy)th...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189622(CHEMBL208672 | {1-methyl-3-[2-(4-phenoxy-phenoxy)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189623(CHEMBL208880 | N-{3-[2-(4-isopropoxy-phenylsulfany...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189630(CHEMBL377212 | N-(4-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189619(1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-pr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189628((S)-(-)-{3-[2-(4-isopropoxy-phenoxy)-thiazol-4-yl]...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189626(CHEMBL209279 | N-(1-cyclopropyl-3-(2-(4-isopropoxy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189625((R)-(+)-{3-[2-(4-isopropoxy-phenoxy)-thiazol-5-yl]...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed