Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50037768
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190927(CHEMBL214513 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190919(CHEMBL386454 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190948(CHEMBL442064 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190943(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-((S)-1-(...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190931(CHEMBL265255 | N-((S)-1-((R)-3-(cyclopentylamino)p...)
Affinity DataKi:  2nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190922(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-(tetrah...)
Affinity DataKi:  2nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190941(CHEMBL387013 | N-((S)-1-((R)-3-(3-cyclohexylpropyl...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190940(CHEMBL383933 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190929(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-(methyl...)
Affinity DataKi:  3nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190918(CHEMBL215067 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190925(4'-Ethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-...)
Affinity DataKi:  4nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190920(4'-ethyl-biphenyl-4-carboxylic acid {(S)-1-[(R)-3-...)
Affinity DataKi:  4nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190947(4'-ethyl-biphenyl-4-carboxylic acid {(S)-1-[(R)-3-...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190921(CHEMBL267797 | N-((S)-1-((R)-3-(dimethylamino)pyrr...)
Affinity DataKi:  5nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190934(4'-ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-...)
Affinity DataKi:  5nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190932(4'-methoxy-2'-methyl-biphenyl-4-carboxylic acid {(...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190944(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-(methyl...)
Affinity DataKi:  6nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190933(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-((tetra...)
Affinity DataKi:  8nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190936(5-(4-methoxyphenyl)-N-methyl-N-((S)-1-((R)-3-(tetr...)
Affinity DataKi:  10nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190939(4'-ethyl-biphenyl-4-carboxylic acid [(S)-1-((R)-3-...)
Affinity DataKi:  11nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190938(5-(4-ethylphenyl)-N-((S)-1-((R)-3-(isopropylamino)...)
Affinity DataKi:  11nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190935(4'-ethyl-biphenyl-4-carboxylic acid {(S)-1-[(R)-3-...)
Affinity DataKi:  14nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190923(CHEMBL386969 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  16nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190930(4'-ethyl-biphenyl-4-carboxylic acid [(S)-1-((R)-3-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190928(CHEMBL384234 | N-((S)-1-((R)-3-(3-cyclohexylpropyl...)
Affinity DataKi:  21nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190265(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  22nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190942(CHEMBL384145 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  25nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190937(4'-ethyl-biphenyl-4-carboxylic acid {(S)-1-[(R)-3-...)
Affinity DataKi:  32nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190924(CHEMBL425082 | N-((S)-1-((R)-3-(3-cyclohexylpropyl...)
Affinity DataKi:  60nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190945(4'-ethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-...)
Affinity DataKi:  69nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190926(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-(methyl...)
Affinity DataKi:  500nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190946(CHEMBL214649 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity to MCHR1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190918(CHEMBL215067 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  900nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190942(CHEMBL384145 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190931(CHEMBL265255 | N-((S)-1-((R)-3-(cyclopentylamino)p...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190927(CHEMBL214513 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190948(CHEMBL442064 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190920(4'-ethyl-biphenyl-4-carboxylic acid {(S)-1-[(R)-3-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190943(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-((S)-1-(...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190940(CHEMBL383933 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190922(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-(tetrah...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190919(CHEMBL386454 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190933(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-((tetra...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190938(5-(4-ethylphenyl)-N-((S)-1-((R)-3-(isopropylamino)...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190934(4'-ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190925(4'-Ethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190923(CHEMBL386969 | N-((S)-1-((R)-3-(4,4-dimethylcycloh...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190939(4'-ethyl-biphenyl-4-carboxylic acid [(S)-1-((R)-3-...)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190944(5-(4-ethylphenyl)-N-methyl-N-((S)-1-((R)-3-(methyl...)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190935(4'-ethyl-biphenyl-4-carboxylic acid {(S)-1-[(R)-3-...)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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