Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50018169
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192278((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50:  24nMAssay Description:Inhibition of NK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191814((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of NK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191813((2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-(4-fluor...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192275((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191813((2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-(4-fluor...)
Affinity DataIC50:  50nMAssay Description:Inhibition of NK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191814((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  59nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192278((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50:  72nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191813((2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-(4-fluor...)
Affinity DataIC50:  80nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192270((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192271(CHEMBL211092 | trans-(S)-N-(3,5-bis(trifluoromethy...)
Affinity DataIC50:  140nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192278((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50:  150nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192266((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187053((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  180nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187048((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192265((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-...)
Affinity DataIC50:  320nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192274((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-...)
Affinity DataIC50:  440nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192269(CHEMBL379742 | cis-(S)-N-(3,5-bis(trifluoromethyl)...)
Affinity DataIC50:  700nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50:  720nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192273((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50:  780nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187052((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  830nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192267((R)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  930nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192272((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192268((R)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192279((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192276((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192277((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed