Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 3312
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31270(CHEMBL360141 | isoindolinone scaffold, 65)
Affinity DataIC50:  1.44E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31251(CHEMBL178106 | isoindolinone scaffold, 40)
Affinity DataIC50:  1.79E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31230(CHEMBL179549 | isoindolinone scaffold, 16)
Affinity DataIC50:  2.70E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31241(isoindolinone scaffold, 30)
Affinity DataIC50:  5.80E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31268(isoindolinone scaffold, 63)
Affinity DataIC50:  6.43E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31231(CHEMBL360920 | isoindolinone scaffold, 17)
Affinity DataIC50:  6.60E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31266(isoindolinone scaffold, 61)
Affinity DataIC50:  6.97E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31232(CHEMBL179114 | isoindolinone scaffold, 18)
Affinity DataIC50:  7.00E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31262(isoindolinone scaffold, 57)
Affinity DataIC50:  7.00E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31264(isoindolinone scaffold, 59)
Affinity DataIC50:  7.01E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31265(isoindolinone scaffold, 60)
Affinity DataIC50:  7.02E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31267(isoindolinone scaffold, 62)
Affinity DataIC50:  7.43E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31236(isoindolinone scaffold, 22)
Affinity DataIC50:  7.80E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31237(isoindolinone scaffold, 24)
Affinity DataIC50:  7.90E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31229(isoindolinone scaffold, 15)
Affinity DataIC50:  8.50E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31258(isoindolinone scaffold, 49)
Affinity DataIC50:  8.80E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31228(CHEMBL182052 | isoindolinone scaffold, 14)
Affinity DataIC50:  9.00E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31227(CHEMBL181688 | isoindolinone scaffold, 13)
Affinity DataIC50:  9.20E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31246(isoindolinone scaffold, 35)
Affinity DataIC50:  9.60E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31245(isoindolinone scaffold, 34)
Affinity DataIC50:  9.70E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31271(isoindolinone scaffold, 67)
Affinity DataIC50:  1.03E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31269(isoindolinone scaffold, 64)
Affinity DataIC50:  1.03E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31247(isoindolinone scaffold, 36)
Affinity DataIC50:  1.16E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31256(isoindolinone scaffold, 47)
Affinity DataIC50:  1.81E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31249(isoindolinone scaffold, 38)
Affinity DataIC50:  1.91E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31242(isoindolinone scaffold, 31)
Affinity DataIC50:  2.06E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31244(isoindolinone scaffold, 33)
Affinity DataIC50:  2.14E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31243(isoindolinone scaffold, 32)
Affinity DataIC50:  2.21E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31250(isoindolinone scaffold, 39)
Affinity DataIC50:  2.32E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31248(isoindolinone scaffold, 37)
Affinity DataIC50:  2.43E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31259(isoindolinone scaffold, 50)
Affinity DataIC50:  2.75E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31239(isoindolinone scaffold, 26)
Affinity DataIC50:  2.81E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31233(isoindolinone scaffold, 19)
Affinity DataIC50:  2.84E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31263(isoindolinone scaffold, 58)
Affinity DataIC50:  2.90E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31238(isoindolinone scaffold, 25)
Affinity DataIC50:  3.11E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31240(isoindolinone scaffold, 28)
Affinity DataIC50:  3.15E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31253(isoindolinone scaffold, 43)
Affinity DataIC50:  3.26E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31252(isoindolinone scaffold, 41)
Affinity DataIC50:  3.45E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31260(isoindolinone scaffold, 51)
Affinity DataIC50:  3.80E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31234(isoindolinone scaffold, 20)
Affinity DataIC50:  3.93E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31257(isoindolinone scaffold, 48)
Affinity DataIC50:  4.13E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31235(isoindolinone scaffold, 21)
Affinity DataIC50:  4.39E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31254(isoindolinone scaffold, 44)
Affinity DataIC50:  4.90E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31255(isoindolinone scaffold, 45)
Affinity DataIC50: >5.00E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Newcastle Upon Tyne

LigandPNGBDBM31261(isoindolinone scaffold, 53)
Affinity DataIC50: >5.00E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed