Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 1810
LigandPNGBDBM14268((2S)-N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-{4-[(5S...)
Affinity DataIC50:  35nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14269((S)-isothiazolidinone | IZD deriv. 2 | N-[(1S)-1-(...)
Affinity DataIC50:  35nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14289(5-{4-[(2S)-2-(1,3-benzothiazol-2-ylamino)-2-[5-(tr...)
Affinity DataIC50:  150nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14292(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3-benz...)
Affinity DataIC50:  230nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13473((5S)-5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3...)
Affinity DataIC50:  270nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
LigandPNGBDBM14293(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3-benz...)
Affinity DataIC50:  280nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14273(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-{[6-(trif...)
Affinity DataIC50:  330nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14282(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(6-metho...)
Affinity DataIC50:  350nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14295(5-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3-benzoth...)
Affinity DataIC50:  400nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14290(5-{4-[(2S)-2-(1,3-benzothiazol-2-ylamino)-2-(5-chl...)
Affinity DataIC50:  410nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14277(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(5-fluor...)
Affinity DataIC50:  420nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14279(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(6-chlor...)
Affinity DataIC50:  440nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14296(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3-benz...)
Affinity DataIC50:  460nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14284(2-{[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-[4-(1,1,3-t...)
Affinity DataIC50:  470nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14291(2-[(1S)-1-(1,3-benzothiazol-2-ylamino)-2-[4-(1,1,3...)
Affinity DataIC50:  470nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14270((R/S)-isothiazolidinone | 5-{4-[(2S)-2-(1H-1,3-ben...)
Affinity DataIC50:  480nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14276(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(6-fluor...)
Affinity DataIC50:  490nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14286(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(6-bromo...)
Affinity DataIC50:  500nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14283(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(4-metho...)
Affinity DataIC50:  550nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14287(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(5-bromo...)
Affinity DataIC50:  620nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14278(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(4-fluor...)
Affinity DataIC50:  660nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14275(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-{[4-(trif...)
Affinity DataIC50:  740nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14280(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(5-chlor...)
Affinity DataIC50:  970nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14288(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(4-bromo...)
Affinity DataIC50:  1.10E+3nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14285(2-{[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-[4-(1,1,3-t...)
Affinity DataIC50:  1.10E+3nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14274(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-{[5-(trif...)
Affinity DataIC50:  1.30E+3nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14294(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3-benz...)
Affinity DataIC50:  1.60E+3nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14281(5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-[(4-chlor...)
Affinity DataIC50:  2.40E+3nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14271((5R)-5-{4-[(2S)-2-(1H-1,3-benzodiazol-2-yl)-2-(1,3...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed