Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50018739
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198574((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...)
Affinity DataKi:  3.30nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  15nMAssay Description:Inhibition of binding to MCH-R1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198582((S)-4-(2-cyclohexylethyl)-1-(6-((diethylamino)meth...)
Affinity DataKi:  32nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198575(1-((S)-6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  47nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198577((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  93nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198584((S)-4-(4-fluorophenethyl)-1-(6-((4-(trifluoromethy...)
Affinity DataKi:  8.70E+3nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198576((S)-4-(4-fluorophenethyl)-1-(6-(morpholinomethyl)-...)
Affinity DataKi:  1.50E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198572((S)-1-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataKi:  1.60E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198581((S)-4-(4-fluorophenethyl)-1-(6-((4-(methylsulfonyl...)
Affinity DataKi:  3.00E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198571((S)-1-(6-((1H-imidazol-1-yl)methyl)-1,2,3,4-tetrah...)
Affinity DataKi:  5.20E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198583(1-((S)-6-(((2R,6S)-2,6-dimethylpiperidin-1-yl)meth...)
Affinity DataKi:  6.20E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198580(4-{[(6S)-6-{4-[2-(4-fluorophenyl)ethyl]-2-oxopiper...)
Affinity DataKi:  9.40E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198578((S)-4-(4-fluorophenethyl)-1-(6-((2,2,2-trifluoroet...)
Affinity DataKi:  1.00E+5nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198579(2-((((S)-6-(4-(4-fluorophenethyl)-2-oxopiperazin-1...)
Affinity DataKi:  2.70E+5nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198577((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198584((S)-4-(4-fluorophenethyl)-1-(6-((4-(trifluoromethy...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198582((S)-4-(2-cyclohexylethyl)-1-(6-((diethylamino)meth...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198574((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198571((S)-1-(6-((1H-imidazol-1-yl)methyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198576((S)-4-(4-fluorophenethyl)-1-(6-(morpholinomethyl)-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198581((S)-4-(4-fluorophenethyl)-1-(6-((4-(methylsulfonyl...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198575(1-((S)-6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198580(4-{[(6S)-6-{4-[2-(4-fluorophenyl)ethyl]-2-oxopiper...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198579(2-((((S)-6-(4-(4-fluorophenethyl)-2-oxopiperazin-1...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198572((S)-1-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed