Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50037892
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50131434(CHEMBL652 | FLECAINIDE | N-(piperidin-2-ylmethyl)-...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213095((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213095((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213095((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50131434(CHEMBL652 | FLECAINIDE | N-(piperidin-2-ylmethyl)-...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213095((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50131434(CHEMBL652 | FLECAINIDE | N-(piperidin-2-ylmethyl)-...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50017662(2-(Diethylamino)-2',6'-acetoxylidide | 2-(Diethyla...)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50017662(2-(Diethylamino)-2',6'-acetoxylidide | 2-(Diethyla...)
Affinity DataIC50:  1.21E+6nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50017662(2-(Diethylamino)-2',6'-acetoxylidide | 2-(Diethyla...)
Affinity DataIC50:  2.19E+6nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed