Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50020625
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215676(CHEMBL228955 | sodium (3R,5R)-7-(3-(4-fluorophenyl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215666((3R,5R)-7-(3,4-bis(4-fluorophenyl)-1-isopropyl-5-(...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215672(CHEMBL228528 | sodium (3R,5R)-7-(5-(3-fluorophenyl...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215669(CHEMBL389216 | sodium (3R,5R)-7-(5-(3-chlorophenyl...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215673((3R,5R)-7-(5-(benzyl(methyl)carbamoyl)-3-(4-fluoro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215675(CHEMBL389442 | sodium (3R,5R)-7-(5-(2-fluorobenzyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215667(CHEMBL387514 | sodium (3R,5R)-7-(7-benzyl-3-(4-flu...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215678(CHEMBL389443 | sodium (3R,5R)-7-(5-(4-fluorobenzyl...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215668(CHEMBL228667 | sodium; (3R,5R)-7-[1-(4-fluoro-phen...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215674(CHEMBL228954 | sodium (3R,5R)-7-(1-(4-fluorophenyl...)
Affinity DataIC50:  11.7nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215671(CHEMBL389441 | sodium (3R,5R)-7-(5-benzyl-1-(4-flu...)
Affinity DataIC50:  13.9nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215679(CHEMBL389217 | sodium (3R,5R)-7-(1,5-bis(4-fluorop...)
Affinity DataIC50:  16.4nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215677(CHEMBL438662 | sodium (3R,5R)-7-(1-(4-fluorophenyl...)
Affinity DataIC50:  16.7nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215670(CHEMBL228583 | sodium (3R,5R)-7-(5-(3-fluorobenzyl...)
Affinity DataIC50:  37.4nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139181((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotet...)
Affinity DataIC50:  49nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed