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Found 9 Enz. Inhib. hit(s) with all data for entry = 50025403
TargetCholinesterase(Equus caballus (Horse))
Università

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  4nMAssay Description:Inhibition of horse serum butyrylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  9nMAssay Description:Inhibition of rat plasma butyrylcholine esterase in presence of butyrylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat brain acetylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat brain acetylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Università

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of horse serum butyrylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Università

Curated by ChEMBL
LigandPNGBDBM50270498(1-benzoyl-3-((6-chloroimidazo[2,1-b]thiazol-5-yl)m...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of electric eel acetylcholine esterase type V-S in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of rat plasma butyrylcholine esterase in presence of butyrylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Università

Curated by ChEMBL
LigandPNGBDBM50270499(1-acetyl-3-((6-methylimidazo[2,1-b]thiazol-5-yl)me...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of electric eel acetylcholine esterase type V-S in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Università

Curated by ChEMBL
LigandPNGBDBM50270497(1-acetyl-3-((6-chloroimidazo[2,1-b]thiazol-5-yl)me...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of electric eel acetylcholine esterase type V-S in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed