Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50021667
TargetCarboxypeptidase B(Sus scrofa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201438((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Affinity DataKi:  0.420nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase N catalytic chain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201438((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Affinity DataKi:  2nMAssay Description:Inhibition of human plasma carboxypeptidase NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201438((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Affinity DataKi:  4nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226610((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Affinity DataKi:  10nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50109593(2-Benzyl-3-mercapto-propionic acid | 2-Mercaptomet...)
Affinity DataKi:  11nMAssay Description:Inhibition of bovine pancreatic carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226605((+/-)-5-amino-2-((1-propyl-1H-imidazol-4-yl)methyl...)
Affinity DataKi:  46nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226598((S)-2-(2-aminoethylamino)-3-(1-butyl-1H-imidazol-4...)
Affinity DataKi:  70nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226606((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...)
Affinity DataKi:  84nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226597((S)-2-(2-aminoethylamino)-3-(1-isobutyl-1H-imidazo...)
Affinity DataKi:  100nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226611((S)-2-(2-aminoethylamino)-3-(1-(3-hydroxypropyl)-1...)
Affinity DataKi:  111nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226614((S)-2-(2-aminoethylamino)-3-(1-(cyclobutylmethyl)-...)
Affinity DataKi:  124nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226607((+/-)-2-((1H-imidazol-4-yl)methyl)-5-aminopentanoi...)
Affinity DataKi:  140nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226613((S)-2-(2-aminoethylamino)-3-(1-phenethyl-1H-imidaz...)
Affinity DataKi:  140nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226602((S)-2-(2-aminoethylamino)-3-(1-pentyl-1H-imidazol-...)
Affinity DataKi:  160nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B(Sus scrofa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226610((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Affinity DataKi:  206nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226601((2S)-2-[(2-aminoethyl)amino]-3-(1-methyl-1H-imidaz...)
Affinity DataKi:  235nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226599((S)-2-(2-aminoethylamino)-3-(1-ethyl-1H-imidazol-4...)
Affinity DataKi:  250nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226608((S)-2-(2-aminoethylamino)-3-(1-benzyl-1H-imidazol-...)
Affinity DataKi:  269nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226603((+/-)-5-amino-2-(mercaptomethyl)pentanoic acid | C...)
Affinity DataKi:  300nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226600((2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)p...)
Affinity DataKi:  344nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226609((S)-2-(2-aminoethylamino)-3-(1-isopropyl-1H-imidaz...)
Affinity DataKi:  430nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226604(CHEMBL392205 | ent-(2S)-5-amino-2-[(1-n-propyl-1H-...)
Affinity DataKi: >700nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase N catalytic chain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226600((2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human plasma carboxypeptidase NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226612((R)-2-(2-aminoethylamino)-3-(1H-imidazol-4-yl)prop...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed