Compile Data Set for Download or QSAR
maximum 50k data
Found 66 Enz. Inhib. hit(s) with all data for entry = 50021798
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228014(2-[4-((R)-2-{1-(3-fluoro-benzenesulfonylamino)-2-[...)
Affinity DataIC50:  22nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228013(3-fluoro-N-{1-{(R)-5-[2-(3-methanesulfonyl-phenoxy...)
Affinity DataIC50:  23nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228024(3-fluoro-N-{1-[5-(3-phenyl-propyl)-1H-imidazol-2-y...)
Affinity DataIC50:  24nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228013(3-fluoro-N-{1-{(R)-5-[2-(3-methanesulfonyl-phenoxy...)
Affinity DataIC50:  25nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228008(2-[4-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  32nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228038(3-fluoro-N-{1-[(R)-5-(2-fluoro-benzyl)-4,5-dihydro...)
Affinity DataIC50:  38nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189675(CHEMBL436933 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  43nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228024(3-fluoro-N-{1-[5-(3-phenyl-propyl)-1H-imidazol-2-y...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228008(2-[4-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  46nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228014(2-[4-((R)-2-{1-(3-fluoro-benzenesulfonylamino)-2-[...)
Affinity DataIC50:  46nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228036(CHEMBL253269 | N-{1-[5-(3-phenyl-propyl)-1H-imidaz...)
Affinity DataIC50:  51nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228036(CHEMBL253269 | N-{1-[5-(3-phenyl-propyl)-1H-imidaz...)
Affinity DataIC50:  52nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228032(CHEMBL403908 | N-{1-(5-phenyl-1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  61nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228038(3-fluoro-N-{1-[(R)-5-(2-fluoro-benzyl)-4,5-dihydro...)
Affinity DataIC50:  64nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228025(2-[4-((R)-2-{1-(3-fluoro-benzenesulfonylamino)-2-[...)
Affinity DataIC50:  65nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189675(CHEMBL436933 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  67nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228039(3-fluoro-N-{1-((R)-5-phenethyl-4,5-dihydro-1H-imid...)
Affinity DataIC50:  68nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228012(3-fluoro-N-{1-{(R)-5-[3-(3-methanesulfonyl-phenoxy...)
Affinity DataIC50:  84nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228021(3-fluoro-N-{1-(5-phenyl-1H-imidazol-2-yl)-2-[4-(1,...)
Affinity DataIC50:  90nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228032(CHEMBL403908 | N-{1-(5-phenyl-1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228028(3-fluoro-N-{1-(5-phenethyl-1H-imidazol-2-yl)-2-[4-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228029(3-fluoro-N-{1-[5-(4-phenyl-butyl)-1H-imidazol-2-yl...)
Affinity DataIC50:  110nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228025(2-[4-((R)-2-{1-(3-fluoro-benzenesulfonylamino)-2-[...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228020(CHEMBL252710 | N-{1-((R)-5-benzyl-4,5-dihydro-1H-i...)
Affinity DataIC50:  120nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228009(2-[3-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  120nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228039(3-fluoro-N-{1-((R)-5-phenethyl-4,5-dihydro-1H-imid...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228033(CHEMBL253475 | N-{1-((R)-5-benzyl-4,5-dihydro-1H-i...)
Affinity DataIC50:  140nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228020(CHEMBL252710 | N-{1-((R)-5-benzyl-4,5-dihydro-1H-i...)
Affinity DataIC50:  150nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228021(3-fluoro-N-{1-(5-phenyl-1H-imidazol-2-yl)-2-[4-(1,...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228026(2-[4-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228012(3-fluoro-N-{1-{(R)-5-[3-(3-methanesulfonyl-phenoxy...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228019(CHEMBL403681 | N-{1-[5-(4-phenyl-butyl)-1H-imidazo...)
Affinity DataIC50:  160nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228026(2-[4-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  170nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228009(2-[3-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  170nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228034(CHEMBL403680 | N-{1-(5-phenethyl-1H-imidazol-2-yl)...)
Affinity DataIC50:  170nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228010(2-[3-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  170nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228034(CHEMBL403680 | N-{1-(5-phenethyl-1H-imidazol-2-yl)...)
Affinity DataIC50:  170nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228028(3-fluoro-N-{1-(5-phenethyl-1H-imidazol-2-yl)-2-[4-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228019(CHEMBL403681 | N-{1-[5-(4-phenyl-butyl)-1H-imidazo...)
Affinity DataIC50:  200nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228033(CHEMBL253475 | N-{1-((R)-5-benzyl-4,5-dihydro-1H-i...)
Affinity DataIC50:  210nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228027(CHEMBL252277 | N-{1-(5-benzyl-1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228031(CHEMBL254513 | N-{1-(1H-imidazol-2-yl)-2-[4-(1,1,3...)
Affinity DataIC50:  240nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228022(CHEMBL404319 | N-{1-(5-benzyl-1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228029(3-fluoro-N-{1-[5-(4-phenyl-butyl)-1H-imidazol-2-yl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228031(CHEMBL254513 | N-{1-(1H-imidazol-2-yl)-2-[4-(1,1,3...)
Affinity DataIC50:  270nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228022(CHEMBL404319 | N-{1-(5-benzyl-1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228027(CHEMBL252277 | N-{1-(5-benzyl-1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228010(2-[3-(2-{1-(3-fluoro-benzenesulfonylamino)-2-[3-me...)
Affinity DataIC50:  350nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228015(CHEMBL253065 | N-{1-((R)-5-methyl-4,5-dihydro-1H-i...)
Affinity DataIC50:  420nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50228030(CHEMBL403116 | N-{1-((R)-5-phenyl-4,5-dihydro-1H-i...)
Affinity DataIC50:  430nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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