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Found 24 Enz. Inhib. hit(s) with all data for entry = 50022065
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231280(1-(3-cyano-4-fluorophenyl)-6-[4-(3-dimethylaminome...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231282(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(3-dimethyla...)
Affinity DataKi:  3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231275(1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-6-[2-flu...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231284(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(2-dimethyla...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231271(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(2-dimethyl...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231279(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(3-dimethyl...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231283(1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-6-[2-flu...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231270(1-(3-aminobenzo[d]isoxazol-5-yl)-6-(2'-dimethylami...)
Affinity DataKi:  8.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231272(1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimeth...)
Affinity DataKi:  15.9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231269(1-{4-[1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-3-...)
Affinity DataKi:  22.9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231274(1-{4-[1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-3-...)
Affinity DataKi:  26nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231286(1-{4-[1-(3-aminomethylphenyl)-7-fluoro-3-methyl-1H...)
Affinity DataKi:  124nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231268(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(4-dimethyla...)
Affinity DataKi:  147nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231278(1-{4-[1-(3-aminomethylphenyl)-7-fluoro-3-methyl-1H...)
Affinity DataKi:  223nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231281(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(2-dimethyl...)
Affinity DataKi:  231nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231267(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(2-dimethyl...)
Affinity DataKi:  690nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231266(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(3-dimethyla...)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231273(1-{4-[1-(3-aminomethylphenyl)-3-methyl-1H-indazol-...)
Affinity DataKi:  6.85E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231265(1-{4-[1-(3-aminomethylphenyl)-3-methyl-1H-indazol-...)
Affinity DataKi: >1.44E+4nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231277(CHEMBL253991 | N-(4-carbamimidoylbenzyl)-2-(6-(3,5...)
Affinity DataIC50:  52nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231276(3-(1-(2-(4-carbamimidoylbenzylamino)-2-oxoethyl)-5...)
Affinity DataIC50:  118nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM14597(2-[3-Amino-3-fluoro-4-(isopropylamino)-1,1-bipheny...)
Affinity DataIC50:  340nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed