TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at human PAR1 in HCASMC assessed as inhibition of thrombin-induced calcium effluxMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Antagonist activity at human PAR1 in HCASMC assessed as inhibition of thrombin-induced thymidine incorporationMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 367nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at PAR1 in human platelets assessed as inhibition of haTRAP-induced platelet aggregationMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Antagonist activity at PAR1 in human platelets assessed as inhibition of thrombin-induced platelet aggregationMore data for this Ligand-Target Pair