Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 3115
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28239(2-(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2...)
Affinity DataIC50:  2nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28238(2-(7-{5-[(4-fluorophenyl)methyl]-4H-1,2,4-triazol-...)
Affinity DataIC50:  11nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28236(CHEMBL199145 | N-[(4-fluorophenyl)methyl]-8-hydrox...)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM23402(5-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(4-fluoropheny...)
Affinity DataIC50:  13nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28233(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  42nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28232(7-(5-benzyl-1,3,4-oxadiazol-2-yl)-1,6-naphthyridin...)
Affinity DataIC50:  130nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28222(7-{5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  130nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28224(7-{5-[(4-fluorophenyl)methyl]-4H-1,2,4-triazol-3-y...)
Affinity DataIC50:  130nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28223(7-(5-benzyl-4H-1,2,4-triazol-3-yl)-1,6-naphthyridi...)
Affinity DataIC50:  360nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28225(7-{5-[(4-chlorophenyl)methyl]-4H-1,2,4-triazol-3-y...)
Affinity DataIC50:  640nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28221(7-(5-benzyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin...)
Affinity DataIC50:  950nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28226(7-{5-[(3-chlorophenyl)methyl]-4H-1,2,4-triazol-3-y...)
Affinity DataIC50:  1.03E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28229(7-[5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]-1,6-na...)
Affinity DataIC50:  2.40E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28227(7-{5-[(3-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-...)
Affinity DataIC50:  2.80E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28231(7-[5-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-yl]-1...)
Affinity DataIC50:  3.50E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28230(7-[5-(pyridin-4-ylmethyl)-4H-1,2,4-triazol-3-yl]-1...)
Affinity DataIC50:  4.60E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28228(7-{5-[(3,4-dimethoxyphenyl)methyl]-4H-1,2,4-triazo...)
Affinity DataIC50:  6.30E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28234(7-{5-[(4-fluorophenyl)methyl]-1-methyl-1H-1,2,4-tr...)
Affinity DataIC50:  7.90E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28237(2-(7-{5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28220(7-(5-phenyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28235(7-{3-[(4-fluorophenyl)methyl]-1-methyl-1H-1,2,4-tr...)
Affinity DataIC50: >5.00E+5nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed