Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 3280
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30337(3-aryl isoxazole analog, 7b)
Affinity DataIC50:  45nM EC50:  102nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1...)
Affinity DataIC50:  64nM EC50:  900nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30336(3-aryl isoxazole analog, 7a)
Affinity DataIC50:  94nM EC50:  900nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30334(3-aryl isoxazole analog, 6c)
Affinity DataIC50:  170nM EC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30333(3-aryl isoxazole analog, 6b)
Affinity DataIC50:  250nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30335(3-aryl isoxazole analog, 6d | CHEMBL469135)
Affinity DataIC50:  690nM EC50:  9.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30342(3-aryl isoxazole analog, 7g)
Affinity DataIC50:  750nM EC50:  2.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30341(3-aryl isoxazole analog, 7f)
Affinity DataIC50:  880nM EC50:  4.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30338(3-aryl isoxazole analog, 7c)
Affinity DataIC50:  1.10E+3nM EC50:  5.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30340(3-aryl isoxazole analog, 7e)
Affinity DataIC50:  4.17E+3nM EC50:  1.20E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30343(3-aryl isoxazole analog, 7h)
Affinity DataIC50:  5.16E+3nM EC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30339(3-aryl isoxazole analog, 7d)
Affinity DataIC50:  7.33E+3nM EC50:  7.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed