Compile Data Set for Download or QSAR
maximum 50k data
Found 186 Enz. Inhib. hit(s) with all data for entry = 3330
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31501(substituted biphenyl derivative, 36ao)
Affinity DataIC50:  8nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31499(substituted biphenyl derivative, 36am)
Affinity DataIC50:  9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31462(substituted biphenyl derivative, 36b)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31497(substituted biphenyl derivative, 36ak)
Affinity DataIC50:  9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31488(substituted biphenyl derivative, 36ab)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31468(substituted biphenyl derivative, 36h)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31500(substituted biphenyl derivative, 36an)
Affinity DataIC50:  10nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31487(substituted biphenyl derivative, 36aa)
Affinity DataIC50:  10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31486(substituted biphenyl derivative, 36z)
Affinity DataIC50:  10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31470(substituted biphenyl derivative, 36j)
Affinity DataIC50:  11nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31493(substituted biphenyl derivative, 36ag)
Affinity DataIC50:  11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31489(substituted biphenyl derivative, 36ac)
Affinity DataIC50:  11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31474(substituted biphenyl derivative, 36n)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31467(substituted biphenyl derivative, 36g)
Affinity DataIC50:  13nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31490(substituted biphenyl derivative, 36ad)
Affinity DataIC50:  14nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31502(substituted biphenyl derivative, 36ap)
Affinity DataIC50:  20nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31501(substituted biphenyl derivative, 36ao)
Affinity DataIC50:  20nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31483(substituted biphenyl derivative, 36w)
Affinity DataIC50:  21nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31503(substituted biphenyl derivative, 36aq)
Affinity DataIC50:  24nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31466(substituted biphenyl derivative, 36f)
Affinity DataIC50:  25nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31475(substituted biphenyl derivative, 36o)
Affinity DataIC50:  29nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31461(substituted biphenyl derivative, 24)
Affinity DataIC50:  30nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31500(substituted biphenyl derivative, 36an)
Affinity DataIC50:  33nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  34nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31487(substituted biphenyl derivative, 36aa)
Affinity DataIC50:  35nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31495(substituted biphenyl derivative, 36ai)
Affinity DataIC50:  36nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31487(substituted biphenyl derivative, 36aa)
Affinity DataIC50:  40nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31464(substituted biphenyl derivative, 36d)
Affinity DataIC50:  42nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31471(substituted biphenyl derivative, 36k)
Affinity DataIC50:  45nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31499(substituted biphenyl derivative, 36am)
Affinity DataIC50:  50nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31491(substituted biphenyl derivative, 36ae)
Affinity DataIC50:  50nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31490(substituted biphenyl derivative, 36ad)
Affinity DataIC50:  50nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31473(substituted biphenyl derivative, 36m)
Affinity DataIC50:  52nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31480(substituted biphenyl derivative, 36t)
Affinity DataIC50:  60nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31497(substituted biphenyl derivative, 36ak)
Affinity DataIC50:  60nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31460(substituted biphenyl derivative, 36a)
Affinity DataIC50:  67nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31467(substituted biphenyl derivative, 36g)
Affinity DataIC50:  70nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31491(substituted biphenyl derivative, 36ae)
Affinity DataIC50:  76nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31465(substituted biphenyl derivative, 36e)
Affinity DataIC50:  92nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31463(substituted biphenyl derivative, 36c)
Affinity DataIC50:  97nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31482(substituted biphenyl derivative, 36v)
Affinity DataIC50:  98nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31492(substituted biphenyl derivative, 36af)
Affinity DataIC50:  104nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31489(substituted biphenyl derivative, 36ac)
Affinity DataIC50:  120nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31459(CHEMBL224485 | substituted biphenyl derivative, 21)
Affinity DataIC50:  120nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  127nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31472(substituted biphenyl derivative, 36l)
Affinity DataIC50:  130nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31497(substituted biphenyl derivative, 36ak)
Affinity DataIC50:  130nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31486(substituted biphenyl derivative, 36z)
Affinity DataIC50:  150nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31503(substituted biphenyl derivative, 36aq)
Affinity DataIC50:  150nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31488(substituted biphenyl derivative, 36ab)
Affinity DataIC50:  163nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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