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Compile Data Set for Download or QSAR
maximum 50k data
Found
33
Enz. Inhib. hit(s) with all data for entry = 50030543
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297795
(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297794
(2-(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297796
(4-(cyclohexylmethyl)-6-(2-methoxypyrimidin-5-yl)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297797
(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297798
(4-(cyclohexylmethyl)-6-(pyridin-4-yl)-2-((tetrahyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.900nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297799
(4-(cyclohexylmethyl)-6-(3,5-dimethylisoxazol-4-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297800
(6-(4-fluorophenyl)-4-(4-methoxybenzyl)-2-(2-morpho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297801
(4-(cyclohexylmethyl)-6-(3,4-difluorophenyl)-2-(2-m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297802
(6-(3,4-difluorophenyl)-4-(4-methoxybenzyl)-2-(2-mo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297803
(6-(6-methoxypyridin-3-yl)-4-(2-propoxyethyl)-2-((t...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296252
(6-(6-methoxypyridin-3-yl)-2-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297804
(6-(4-fluorophenyl)-4-(pyridin-3-ylmethyl)-2-((tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.5nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297805
(4-(3,5-difluorobenzyl)-6-(4-fluorophenyl)-2-((tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297806
(4-(cyclohexylmethyl)-6-(6-hydroxypyridin-3-yl)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297807
(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-((tetrah...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297808
(2-(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-3-oxo-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.5nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297809
(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-(2-morph...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.60nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297810
(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-(pyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297811
(2-(6-(6-methoxypyridin-3-yl)-3-oxo-4-(2-propoxyeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297812
(6-(4-fluorophenyl)-4-(pyridin-2-ylmethyl)-2-((tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297813
(6-(4-fluorophenyl)-4-(2-propoxyethyl)-2-((tetrahyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297793
(1-(4-methoxybenzyl)-7-(pyridin-4-yl)quinolin-2(1H)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297814
(6-(2-methoxypyrimidin-5-yl)-2-(2-morpholinoethylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297815
(2-amino-4-(cyclohexylmethyl)-6-(4-fluorophenyl)pyr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297816
(6-(4-fluorophenyl)-2-(2-morpholinoethylamino)-4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297817
(4-(2-propoxyethyl)-6-(pyridin-4-yl)-2-((tetrahydro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297818
(6-(3,5-dimethylisoxazol-4-yl)-2-(2-morpholinoethyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297792
(7-(3,4-difluorophenyl)-4-methyl-1-pentyl-3,4-dihyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297791
(5-amino-7-phenyl-1-propyl-1,6-naphthyridin-4(1H)-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297819
(6-(3,4-difluorophenyl)-4-(2-isopropoxyethyl)-2-(2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 53nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297820
(4-(2-ethoxyethyl)-6-(4-fluorophenyl)-2-((tetrahydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 149nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297821
(6-(4-fluorophenyl)-4-isobutyl-2-((tetrahydro-2H-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 224nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297822
(6-(6-hydroxypyridin-3-yl)-2-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 534nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI