Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50030543
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297795(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297794(2-(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297796(4-(cyclohexylmethyl)-6-(2-methoxypyrimidin-5-yl)-2...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297797(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297798(4-(cyclohexylmethyl)-6-(pyridin-4-yl)-2-((tetrahyd...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297799(4-(cyclohexylmethyl)-6-(3,5-dimethylisoxazol-4-yl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297800(6-(4-fluorophenyl)-4-(4-methoxybenzyl)-2-(2-morpho...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297801(4-(cyclohexylmethyl)-6-(3,4-difluorophenyl)-2-(2-m...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297802(6-(3,4-difluorophenyl)-4-(4-methoxybenzyl)-2-(2-mo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297803(6-(6-methoxypyridin-3-yl)-4-(2-propoxyethyl)-2-((t...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50296252(6-(6-methoxypyridin-3-yl)-2-(2-morpholinoethylamin...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297804(6-(4-fluorophenyl)-4-(pyridin-3-ylmethyl)-2-((tetr...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297805(4-(3,5-difluorobenzyl)-6-(4-fluorophenyl)-2-((tetr...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297806(4-(cyclohexylmethyl)-6-(6-hydroxypyridin-3-yl)-2-(...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297807(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-((tetrah...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297808(2-(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-3-oxo-3...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297809(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-(2-morph...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297810(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-(pyridin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297811(2-(6-(6-methoxypyridin-3-yl)-3-oxo-4-(2-propoxyeth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297812(6-(4-fluorophenyl)-4-(pyridin-2-ylmethyl)-2-((tetr...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297813(6-(4-fluorophenyl)-4-(2-propoxyethyl)-2-((tetrahyd...)
Affinity DataIC50:  22nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297793(1-(4-methoxybenzyl)-7-(pyridin-4-yl)quinolin-2(1H)...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297814(6-(2-methoxypyrimidin-5-yl)-2-(2-morpholinoethylam...)
Affinity DataIC50:  27nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297815(2-amino-4-(cyclohexylmethyl)-6-(4-fluorophenyl)pyr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297816(6-(4-fluorophenyl)-2-(2-morpholinoethylamino)-4-(2...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297817(4-(2-propoxyethyl)-6-(pyridin-4-yl)-2-((tetrahydro...)
Affinity DataIC50:  34nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297818(6-(3,5-dimethylisoxazol-4-yl)-2-(2-morpholinoethyl...)
Affinity DataIC50:  37nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297792(7-(3,4-difluorophenyl)-4-methyl-1-pentyl-3,4-dihyd...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297791(5-amino-7-phenyl-1-propyl-1,6-naphthyridin-4(1H)-o...)
Affinity DataIC50:  51nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297819(6-(3,4-difluorophenyl)-4-(2-isopropoxyethyl)-2-(2-...)
Affinity DataIC50:  53nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297820(4-(2-ethoxyethyl)-6-(4-fluorophenyl)-2-((tetrahydr...)
Affinity DataIC50:  149nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297821(6-(4-fluorophenyl)-4-isobutyl-2-((tetrahydro-2H-py...)
Affinity DataIC50:  224nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297822(6-(6-hydroxypyridin-3-yl)-2-(2-morpholinoethylamin...)
Affinity DataIC50:  534nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed