Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50038968
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301048(3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301053(4-(3-(4-hydroxyphenyl)-3-oxoprop-1-enyl)-5-methoxy...)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301052(3-(2,4-dimethoxy-5-(2-methylbut-3-en-2-yl)phenyl)-...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301050(4-(3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301054(5-methoxy-4-(3-(4-methoxyphenyl)-3-oxoprop-1-enyl)...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301049(3-(2,4-dimethoxy-5-(2-methylbut-3-en-2-yl)phenyl)-...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301047(3-(4-hydroxy-2-methoxy-5-(3-methylbut-3-en-2-yl)ph...)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301055(4-(3-(2,4-dimethoxy-5-(2-methylbut-3-en-2-yl)pheny...)
Affinity DataIC50:  2.92E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301046((E)-3-[4-Hydroxy-2-methoxy-3-(3-methyl-but-2-enyl)...)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50068267((E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-ph...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50241408((2S)-liquiritigenin | 7-HYDROXY-2-(4-HYDROXY-PHENY...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50301051(4-(3-(4-acetoxy-2-methoxy-5-(2-methylbut-3-en-2-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed