Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50004317
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481575(CHEMBL591351)
Affinity DataIC50:  6.14E+3nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481577(CHEMBL591596)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481573(CHEMBL591295)
Affinity DataIC50:  3.44E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481571(CHEMBL591595)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481574(CHEMBL589855)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481570(CHEMBL589505)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481576(CHEMBL589658)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481572(CHEMBL589905)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated NotchdeltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed