Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50031154
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308167((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308181((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  3.06nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308183(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...)
Affinity DataKi:  3.55nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308177(1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...)
Affinity DataKi:  3.62nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308175(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...)
Affinity DataKi:  4.27nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  4.46nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308178(1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...)
Affinity DataKi:  4.52nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308179(1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...)
Affinity DataKi:  8.04nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308180(1-{3-[(4-Isopropylphenyl)sulfonyl]-1H-indazol-5-yl...)
Affinity DataKi:  13.1nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308170((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataKi:  13.7nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308176(1-[3-(2-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...)
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308181((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308169((3R)-1-[1-Methyl-3-(naphthalen-1-ylsulfonyl)-1H-in...)
Affinity DataKi:  21.1nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308168((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...)
Affinity DataKi:  24.4nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308171((3R)-1-[1-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi:  36.9nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308173((3R)-1-[2-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataKi:  48.7nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308172((3R)-1-[2-Methyl-3-(naphthalen-1-ylsulfonyl)-2H-in...)
Affinity DataKi:  54.3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308174((3R)-1-[2-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi:  75.8nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308178(1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308183(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...)
Affinity DataKi:  97.9nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308175(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308169((3R)-1-[1-Methyl-3-(naphthalen-1-ylsulfonyl)-1H-in...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308170((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataKi:  191nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308174((3R)-1-[2-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  274nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308167((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...)
Affinity DataKi:  423nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308179(1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...)
Affinity DataKi:  442nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308172((3R)-1-[2-Methyl-3-(naphthalen-1-ylsulfonyl)-2H-in...)
Affinity DataKi:  455nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308177(1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...)
Affinity DataKi:  493nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308168((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...)
Affinity DataKi:  583nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308176(1-[3-(2-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  2.27E+3nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  2.91E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308173((3R)-1-[2-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataKi: >3.30E+3nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308171((3R)-1-[1-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi: >3.30E+3nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  4.73E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi:  6.04E+3nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to alpha2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308180(1-{3-[(4-Isopropylphenyl)sulfonyl]-1H-indazol-5-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308181((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataIC50:  12.5nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308182((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...)
Affinity DataIC50:  15.7nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308183(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...)
Affinity DataIC50:  16.5nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308168((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...)
Affinity DataIC50:  17.5nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308177(1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...)
Affinity DataIC50:  26.7nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  27.5nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308175(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308179(1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...)
Affinity DataIC50:  33.7nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308167((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...)
Affinity DataIC50:  39.6nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308180(1-{3-[(4-Isopropylphenyl)sulfonyl]-1H-indazol-5-yl...)
Affinity DataIC50:  51.7nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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