Compile Data Set for Download or QSAR
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Found 96 Enz. Inhib. hit(s) with all data for entry = 50041810
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118772(2-(Oxalyl-amino)-6-oxo-4,5,6,7-tetrahydro-benzo[b]...)
Affinity DataKi:  1.29E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118771(2-(carboxyformamido)-6-hydroxy-4,5,6,7-tetrahydrob...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416041(CHEMBL198589)
Affinity DataKi:  2.19E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118765(3-(carboxyformamido)-5-(4-(carboxymethoxy)phenyl)t...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118782(3-(carboxyformamido)-5-(4-hydroxyphenyl)thiophene-...)
Affinity DataKi:  4.47E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118780(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Affinity DataKi:  4.68E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118783(2-(Oxalyl-amino)-6-oxo-4,5,6,7-tetrahydro-6lambda*...)
Affinity DataKi:  5.13E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118763(2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lam...)
Affinity DataKi:  6.03E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118758(5-(3-Amino-phenyl)-3-(oxalyl-amino)-thiophene-2-ca...)
Affinity DataKi:  6.03E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118756(3-(carboxyformamido)-5-(3,5-dimethoxyphenyl)thioph...)
Affinity DataKi:  7.94E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118740(3-(carboxyformamido)-5-(4-fluorophenyl)thiophene-2...)
Affinity DataKi:  7.94E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118796(6-(OXALYL-AMINO)-1H-INDOLE-5-CARBOXYLIC ACID | 6-(...)
Affinity DataKi:  7.94E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118762(2-(Oxalyl-amino)-4,5,6,7-tetrahydro-benzo[b]thioph...)
Affinity DataKi:  8.13E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118787(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiop...)
Affinity DataKi:  8.32E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118759(3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-...)
Affinity DataKi:  8.91E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416040(CHEMBL383570)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118760(3-(carboxyformamido)-5-(4-chlorophenyl)thiophene-2...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118764(3-(carboxyformamido)-5-(thiophen-3-yl)thiophene-2-...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118753(2-(Oxalyl-amino)-5,6-dihydro-4H-cyclopenta[b]thiop...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118788(3-(carboxyformamido)-5-(3-methoxyphenyl)thiophene-...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118785(2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118747(3-(Oxalyl-amino)-5-phenyl-thiophene-2-carboxylic a...)
Affinity DataKi:  1.29E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118781(3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene...)
Affinity DataKi:  1.29E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118778(5-iodo-2-(oxaloamino)benzoic acid | CHEMBL336908)
Affinity DataKi:  1.41E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  1.41E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118776(4-(Oxalyl-amino)-biphenyl-3-carboxylic acid | 4-(c...)
Affinity DataKi:  1.41E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118745(5-(4-(benzyloxy)phenyl)-3-(carboxyformamido)thioph...)
Affinity DataKi:  1.58E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118751(6-(Oxalyl-amino)-1H-indole-7-carboxylic acid | 6-(...)
Affinity DataKi:  1.82E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118789(2-(oxaloamino)benzoic acid | CHEMBL139050)
Affinity DataKi:  2.29E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118769(3-(carboxyformamido)-5-(3,4-dimethoxyphenyl)thioph...)
Affinity DataKi:  2.51E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118775(3-(Oxalyl-amino)-5-(4-phenoxy-phenyl)-thiophene-2-...)
Affinity DataKi:  2.57E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118779(3-(Oxalyl-amino)-thiophene-2-carboxylic acid | 3-(...)
Affinity DataKi:  3.72E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118795(4-(Oxalyl-amino)-thiophene-3-carboxylic acid | 4-(...)
Affinity DataKi:  7.59E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118749(2-(Oxalyl-amino)-thiophene-3-carboxylic acid | 2-(...)
Affinity DataKi:  1.07E+5nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118746(3-(Oxalyl-amino)-isonicotinic acid | 3-(carboxyfor...)
Affinity DataKi:  1.58E+5nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118777(2-(1-carboxy-N-methylformamido)benzoic acid | 2-(M...)
Affinity DataKi:  1.10E+6nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118768(2-(carboxyformamido)-3-methylbenzoic acid | 3-Meth...)
Affinity DataKi:  1.26E+6nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118757(2-(carboxyformamido)-6-methylbenzoic acid | 2-Meth...)
Affinity DataKi:  1.70E+6nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118743(3-(carboxyformamido)-4-methylthiophene-2-carboxyli...)
Affinity DataKi:  2.00E+6nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50086972(2-{4-[4-(2-benzyl-1-benzothiophen-3-yl)phenyl]-2,6...)
Affinity DataIC50:  25.1nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416047(CHEMBL1083714)
Affinity DataIC50:  25.1nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50086950(2-[4-[4-(2-benzylbenzo[b]thiophen-3-yl)phenyl]-2,6...)
Affinity DataIC50:  25.1nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50086975(Benzothiophene derivative | CHEMBL25628 | [4-(2-Be...)
Affinity DataIC50:  28.2nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50086954(CHEMBL278092 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)...)
Affinity DataIC50:  28.8nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416048(CHEMBL1086226)
Affinity DataIC50:  38.0nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416043(CHEMBL1086227)
Affinity DataIC50:  42.7nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50086969(CHEMBL24607 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)-...)
Affinity DataIC50:  46.8nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50086967(CHEMBL284765 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)...)
Affinity DataIC50:  52.5nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416032(CHEMBL1082298)
Affinity DataIC50:  52.5nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50416051(CHEMBL1082297)
Affinity DataIC50:  52.5nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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