Compile Data Set for Download or QSAR
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Found 19 Enz. Inhib. hit(s) with all data for entry = 50039184
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040((2E)-1-(3',4'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-Hydroxyphenyl)-3-(1-naphtyl)-2-propen-1...)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828((2E)-1-(3'-Methoxy-4'-hydroxyphenyl)-3-(2-naphtyl)...)
Affinity DataKi:  1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataKi:  2.13E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320829((oxalylamino-methylene)-thiophenesulfonamide | CHE...)
Affinity DataIC50:  440nMAssay Description:Inhibition of N-terminal histidine-tagged Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040((2E)-1-(3',4'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50159781(CHEMBL183648 | molybdate)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50284960(CHEMBL50626 | H3VO4 | Vanadiumsaeure | [VO(OH)3] |...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50080994(CHEMBL85943 | sodium tungstate)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataIC50:  3.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-Hydroxyphenyl)-3-(1-naphtyl)-2-propen-1...)
Affinity DataIC50:  5.02E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828((2E)-1-(3'-Methoxy-4'-hydroxyphenyl)-3-(2-naphtyl)...)
Affinity DataIC50:  5.37E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828((2E)-1-(3'-Methoxy-4'-hydroxyphenyl)-3-(2-naphtyl)...)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-Hydroxyphenyl)-3-(1-naphtyl)-2-propen-1...)
Affinity DataIC50:  1.58E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataIC50:  2.14E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040((2E)-1-(3',4'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50:  1.26E+6nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed