Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50039224
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50077263((-)-Phenethylcymserine | (4-Isopropyl-phenyl)-carb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10611((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321918((3aS)-1,1,3a,8-tetramethyl-5-(o-tolylcarbamoyloxy)...)
Affinity DataIC50:  14.6nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  18.8nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10622((-)-Phenserine | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321917((3aS)-1,1,3a,8-tetramethyl-5-(phenylcarbamoyloxy)-...)
Affinity DataIC50:  25.4nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321916((3aS)-1,1,3a,8-tetramethyl-5-(methylcarbamoyloxy)-...)
Affinity DataIC50:  26.1nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  27.9nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321919((3aS)-5-(4-isopropylphenylcarbamoyloxy)-1,1,3a,8-t...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10613((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321920((3aS)-5-(4-isopropylphenylcarbamoyloxy)-1,3a,8-tri...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321916((3aS)-1,1,3a,8-tetramethyl-5-(methylcarbamoyloxy)-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321918((3aS)-1,1,3a,8-tetramethyl-5-(o-tolylcarbamoyloxy)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321919((3aS)-5-(4-isopropylphenylcarbamoyloxy)-1,1,3a,8-t...)
Affinity DataIC50:  145nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321917((3aS)-1,1,3a,8-tetramethyl-5-(phenylcarbamoyloxy)-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321920((3aS)-5-(4-isopropylphenylcarbamoyloxy)-1,3a,8-tri...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321915(1-methyl-3-(phenylcarbamoyloxy)pyridinium bromide ...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10613((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50:  760nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10622((-)-Phenserine | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321913(CHEMBL1172830 | N,N,N-trimethyl-3-(phenylcarbamoyl...)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10611((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321912(3-(dimethylamino)phenyl phenylcarbamate | CHEMBL11...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321913(CHEMBL1172830 | N,N,N-trimethyl-3-(phenylcarbamoyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321912(3-(dimethylamino)phenyl phenylcarbamate | CHEMBL11...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50077263((-)-Phenethylcymserine | (4-Isopropyl-phenyl)-carb...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321914(CHEMBL1173543 | pyridin-3-yl phenylcarbamate)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321915(1-methyl-3-(phenylcarbamoyloxy)pyridinium bromide ...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50321914(CHEMBL1173543 | pyridin-3-yl phenylcarbamate)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed