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Found 24 Enz. Inhib. hit(s) with all data for entry = 50032258
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  60nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326318((E/Z)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-(pyr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326309((Z)-1-(4-(Methylsulfonyl)phenyl)-2,3-diphenylprop-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326316((E)-3-(4-Hydroxyphenyl)-1-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  80nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326308((E)-1-(4-(Methylsulfonyl)phenyl)-2,3-diphenylprop-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326317((E)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-(thiop...)
Affinity DataIC50:  130nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326311((Z)-3-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326310((E)-3-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl...)
Affinity DataIC50:  190nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326313((Z)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-p-toly...)
Affinity DataIC50:  210nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326315((Z)-3-(4-Methoxyphenyl)-1-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  210nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326314((E)-3-(4-Methoxyphenyl)-1-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  220nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326312((E)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-p-toly...)
Affinity DataIC50:  280nMAssay Description:Inhibition of ovine COX2 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326312((E)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-p-toly...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326314((E)-3-(4-Methoxyphenyl)-1-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326313((Z)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-p-toly...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326318((E/Z)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-(pyr...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326310((E)-3-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326317((E)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-(thiop...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326308((E)-1-(4-(Methylsulfonyl)phenyl)-2,3-diphenylprop-...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326309((Z)-1-(4-(Methylsulfonyl)phenyl)-2,3-diphenylprop-...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326316((E)-3-(4-Hydroxyphenyl)-1-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326315((Z)-3-(4-Methoxyphenyl)-1-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326311((Z)-3-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl...)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of ovine COX1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed