Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50032597
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(CHEMBL1290636 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-ph...)
Affinity DataIC50:  0.950nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(CHEMBL1289203 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(CHEMBL1290637 | N-(2-oxo-2-((3S,4S)-1-(cis-4-pheny...)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(CHEMBL1290636 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-ph...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(CHEMBL1290637 | N-(2-oxo-2-((3S,4S)-1-(cis-4-pheny...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(CHEMBL1289203 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(CHEMBL1289083 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(CHEMBL1289203 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(CHEMBL1290637 | N-(2-oxo-2-((3S,4S)-1-(cis-4-pheny...)
Affinity DataIC50:  2.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(CHEMBL1289083 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  3.80nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(CHEMBL1290636 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-ph...)
Affinity DataIC50:  6.5nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(CHEMBL1290412 | N-(2-((3S,4S)-4-hydroxy-1-(cis-4-p...)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  7.80nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  9.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(CHEMBL1289083 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(CHEMBL1290412 | N-(2-((3S,4S)-4-hydroxy-1-(cis-4-p...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(CHEMBL1289203 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(CHEMBL1290636 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-ph...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331725(CHEMBL1288324 | N-(2-((3S,4S)-4-(benzyloxy)-1-(cis...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331724(CHEMBL1290754 | N-(2-((3S,4S)-4-butoxy-1-(cis-4-ph...)
Affinity DataIC50:  47nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331725(CHEMBL1288324 | N-(2-((3S,4S)-4-(benzyloxy)-1-(cis...)
Affinity DataIC50:  51nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331724(CHEMBL1290754 | N-(2-((3S,4S)-4-butoxy-1-(cis-4-ph...)
Affinity DataIC50:  54nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331719(CHEMBL1290186 | N-(2-((3S,4S)-4-hydroxy-1-(cis-3-p...)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(CHEMBL1290637 | N-(2-oxo-2-((3S,4S)-1-(cis-4-pheny...)
Affinity DataIC50:  158nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(CHEMBL1290412 | N-(2-((3S,4S)-4-hydroxy-1-(cis-4-p...)
Affinity DataIC50:  186nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(CHEMBL1290412 | N-(2-((3S,4S)-4-hydroxy-1-(cis-4-p...)
Affinity DataIC50:  265nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(CHEMBL1289083 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  444nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331721(CHEMBL1290522 | N-(2-((3S,4S)-4-hydroxy-1-(1-pheny...)
Affinity DataIC50:  649nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mouse CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331716(CHEMBL1290411 | N-(2-((3S,4S)-4-hydroxy-1-(trans-3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331717(CHEMBL1290297 | N-(2-((3S,4S)-4-hydroxy-1-(cis-3-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331718(CHEMBL1290296 | N-(2-((3S,4S)-4-hydroxy-1-(trans-3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331720(CHEMBL1290521 | N-(2-((3S,4S)-4-hydroxy-1-(trans-4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(CHEMBL1290412 | N-(2-((3S,4S)-4-hydroxy-1-(cis-4-p...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(CHEMBL1290636 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-ph...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of mouse CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Rattus norvegicus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of rat CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(CHEMBL1289203 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCCR2 protein(Macaca fascicularis)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of cynomolgus CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(CHEMBL1289083 | N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed