Compile Data Set for Download or QSAR
maximum 50k data
Found 80 Enz. Inhib. hit(s) with all data for entry = 50032739
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333952(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333972(CHEMBL1644605 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataKi:  119nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333954(CHEMBL1644611 | exo-3-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataKi:  1.62E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333953(2-(3-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)-5-...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)
Affinity DataKi:  7.08E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333975(CHEMBL1644608 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333960(CHEMBL1644477 | exo-(1R,5S)-3-(3-iodophenoxy)-8-az...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333959(CHEMBL1644476 | exo-(1R,5S)-3-(3-bromophenoxy)-8-a...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333977(CHEMBL1644610 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333957(CHEMBL1644474 | exo-(1R,5S)-3-(3-chlorophenoxy)-8-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333966(CHEMBL1644483 | exo-3-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333952(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333969(CHEMBL1644602 | exo-(1R,5S)-3-(5-chlorobiphenyl-3-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333974(CHEMBL1644607 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)
Affinity DataIC50:  31nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333956(CHEMBL1644473 | exo-(1R,5S)-3-(4-chlorophenoxy)-8-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333977(CHEMBL1644610 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  48nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333978(CHEMBL1644471 | exo-(1R,5S)-3-phenoxy-8-azabicyclo...)
Affinity DataIC50:  54nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333973(CHEMBL1644606 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)
Affinity DataIC50:  60nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333961(CHEMBL1644478 | exo-(1R,5S)-3-(3-fluorophenoxy)-8-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333970(CHEMBL1644603 | exo-(1R,5S)-3-(5-fluorobiphenyl-3-...)
Affinity DataIC50:  85nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333955(CHEMBL1644472 | exo-(1R,5S)-8-methyl-3-phenoxy-8-a...)
Affinity DataIC50:  86nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333963(CHEMBL1644480 | exo-(1R,5S)-3-(3-nitrophenoxy)-8-a...)
Affinity DataIC50:  86nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333972(CHEMBL1644605 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  90nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333963(CHEMBL1644480 | exo-(1R,5S)-3-(3-nitrophenoxy)-8-a...)
Affinity DataIC50:  91nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333962(CHEMBL1644479 | exo-(1R,5S)-3-(m-tolyloxy)-8-azabi...)
Affinity DataIC50:  92nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333964(CHEMBL1644481 | exo-(1R,5S)-3-(3-(trifluoromethyl)...)
Affinity DataIC50:  99nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333971(CHEMBL1644604 | exo-5-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  100nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333973(CHEMBL1644606 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)
Affinity DataIC50:  105nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333960(CHEMBL1644477 | exo-(1R,5S)-3-(3-iodophenoxy)-8-az...)
Affinity DataIC50:  106nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333966(CHEMBL1644483 | exo-3-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  126nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333964(CHEMBL1644481 | exo-(1R,5S)-3-(3-(trifluoromethyl)...)
Affinity DataIC50:  128nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333968(CHEMBL1644601 | exo-(1R,5S)-3-(5-bromobiphenyl-3-y...)
Affinity DataIC50:  132nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333957(CHEMBL1644474 | exo-(1R,5S)-3-(3-chlorophenoxy)-8-...)
Affinity DataIC50:  135nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333959(CHEMBL1644476 | exo-(1R,5S)-3-(3-bromophenoxy)-8-a...)
Affinity DataIC50:  136nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333971(CHEMBL1644604 | exo-5-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  148nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333973(CHEMBL1644606 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)
Affinity DataIC50:  173nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333958(CHEMBL1644475 | exo-(1R,5S)-3-(2-chlorophenoxy)-8-...)
Affinity DataIC50:  188nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333959(CHEMBL1644476 | exo-(1R,5S)-3-(3-bromophenoxy)-8-a...)
Affinity DataIC50:  201nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333972(CHEMBL1644605 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)
Affinity DataIC50:  208nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333965(CHEMBL1644482 | exo-(1R,5S)-3-(3-methoxyphenoxy)-8...)
Affinity DataIC50:  222nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333956(CHEMBL1644473 | exo-(1R,5S)-3-(4-chlorophenoxy)-8-...)
Affinity DataIC50:  347nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333965(CHEMBL1644482 | exo-(1R,5S)-3-(3-methoxyphenoxy)-8...)
Affinity DataIC50:  369nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333957(CHEMBL1644474 | exo-(1R,5S)-3-(3-chlorophenoxy)-8-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333955(CHEMBL1644472 | exo-(1R,5S)-8-methyl-3-phenoxy-8-a...)
Affinity DataIC50:  437nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333969(CHEMBL1644602 | exo-(1R,5S)-3-(5-chlorobiphenyl-3-...)
Affinity DataIC50:  452nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333974(CHEMBL1644607 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)
Affinity DataIC50:  481nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333962(CHEMBL1644479 | exo-(1R,5S)-3-(m-tolyloxy)-8-azabi...)
Affinity DataIC50:  624nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333978(CHEMBL1644471 | exo-(1R,5S)-3-phenoxy-8-azabicyclo...)
Affinity DataIC50:  737nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333961(CHEMBL1644478 | exo-(1R,5S)-3-(3-fluorophenoxy)-8-...)
Affinity DataIC50:  750nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 80 total ) | Next | Last >>
Jump to: