Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50033602
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataKi:  4.60E+3nMAssay Description:Reversible inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataKi:  4.60E+3nMAssay Description:Competitive inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348091(CHEMBL579363 | GNF-PF-1973)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348093(CHEMBL1800274)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348091(CHEMBL579363 | GNF-PF-1973)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of VHXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LMW-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50:  1.18E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348090(CHEMBL1800272)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348094(CHEMBL214303)
Affinity DataIC50:  1.55E+5nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348090(CHEMBL1800272)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348091(CHEMBL579363 | GNF-PF-1973)
Affinity DataIC50:  1.76E+5nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348090(CHEMBL1800272)
Affinity DataIC50:  1.81E+5nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed