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Found 21 Enz. Inhib. hit(s) with all data for entry = 50040406
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393736(CHEMBL2159140)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393730(CHEMBL2159131)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393731(CHEMBL2159136)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393734(CHEMBL2159133)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393733(CHEMBL2159134)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393729(CHEMBL2159130)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393732(CHEMBL2159135)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393738(CHEMBL2159138)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393731(CHEMBL2159136)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393736(CHEMBL2159140)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393735(CHEMBL2159132)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393737(CHEMBL2159139)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393730(CHEMBL2159131)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393733(CHEMBL2159134)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393729(CHEMBL2159130)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393734(CHEMBL2159133)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393735(CHEMBL2159132)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373918(AZITHROMYCIN | Azasite)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using DEF as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393737(CHEMBL2159139)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373918(AZITHROMYCIN | Azasite)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50393732(CHEMBL2159135)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-BQ as substrate preincubated for 5 to 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed