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Found 4 Enz. Inhib. hit(s) with all data for entry = 5636
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College Of Medicine

LigandPNGBDBM92358(HGXPRT Inhibitor, 3)
Affinity DataKi:  0.650nM ΔG°:  -54.5kJ/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College Of Medicine

LigandPNGBDBM92357(HGXPRT Inhibitor, 2)
Affinity DataKi:  10.6nM ΔG°:  -47.3kJ/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Albert Einstein College Of Medicine

LigandPNGBDBM92358(HGXPRT Inhibitor, 3)
Affinity DataKi:  385nM ΔG°:  -38.1kJ/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Albert Einstein College Of Medicine

LigandPNGBDBM92357(HGXPRT Inhibitor, 2)
Affinity DataKi:  4.94E+3nM ΔG°:  -31.5kJ/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed