Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50040421
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393973(CHEMBL2158364)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393967(CHEMBL2158358)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393968(CHEMBL2158359)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393973(CHEMBL2158364)
Affinity DataIC50:  2.98E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393976(CHEMBL2158366)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393974(CHEMBL2158006)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393965(CHEMBL2158356)
Affinity DataIC50:  4.61E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393971(CHEMBL2158362)
Affinity DataIC50:  5.03E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393972(CHEMBL2158363)
Affinity DataIC50:  8.25E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393976(CHEMBL2158366)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393969(CHEMBL2158360)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393975(CHEMBL2158365)
Affinity DataIC50:  9.64E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393974(CHEMBL2158006)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393966(CHEMBL2158357)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393970(CHEMBL2158361)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393967(CHEMBL2158358)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393968(CHEMBL2158359)
Affinity DataIC50:  3.87E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393969(CHEMBL2158360)
Affinity DataIC50:  5.03E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393975(CHEMBL2158365)
Affinity DataIC50:  5.24E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393971(CHEMBL2158362)
Affinity DataIC50:  6.99E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50393965(CHEMBL2158356)
Affinity DataIC50:  7.49E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in insect cells using arachidonic acid as substrate incubated for 1 min prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed