Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 50045938
TargetCytochrome P450 1A2(Homo sapiens (Human))
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed