Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50043046
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435048(CHEMBL2391142)
Affinity DataIC50:  2nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435046(CHEMBL2391140)
Affinity DataIC50:  3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435047(CHEMBL2391299)
Affinity DataIC50:  3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50:  3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435045(CHEMBL2391141)
Affinity DataIC50:  3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50:  6nMAssay Description:Inhibition of mPGES-1 in human fetal fibroblast cells assessed as PGF2alpha level after 50 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435044(CHEMBL2391295)
Affinity DataIC50:  6nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425313(CHEMBL2315853)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435043(CHEMBL2391296)
Affinity DataIC50:  15nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435042(CHEMBL2391297)
Affinity DataIC50:  16nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435041(CHEMBL2391294)
Affinity DataIC50:  20nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50:  25nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426957(CHEMBL2325075)
Affinity DataIC50:  33nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425318(CHEMBL2315861)
Affinity DataIC50:  36nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435054(CHEMBL2391289)
Affinity DataIC50:  47nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435056(CHEMBL2391298)
Affinity DataIC50:  49nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435048(CHEMBL2391142)
Affinity DataIC50:  53nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435055(CHEMBL2391293)
Affinity DataIC50:  88nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50:  109nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435047(CHEMBL2391299)
Affinity DataIC50:  119nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435045(CHEMBL2391141)
Affinity DataIC50:  133nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435041(CHEMBL2391294)
Affinity DataIC50:  162nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426957(CHEMBL2325075)
Affinity DataIC50:  174nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50:  180nMAssay Description:Inhibition of mPGES-1 in human 1483 cells assessed as eicosanoid level incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426966(CHEMBL2325080)
Affinity DataIC50:  206nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426966(CHEMBL2325080)
Affinity DataIC50:  206nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425318(CHEMBL2315861)
Affinity DataIC50:  220nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435046(CHEMBL2391140)
Affinity DataIC50:  240nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435044(CHEMBL2391295)
Affinity DataIC50:  261nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435056(CHEMBL2391298)
Affinity DataIC50:  336nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50:  338nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426966(CHEMBL2325080)
Affinity DataIC50:  340nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435055(CHEMBL2391293)
Affinity DataIC50:  510nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435042(CHEMBL2391297)
Affinity DataIC50:  684nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435054(CHEMBL2391289)
Affinity DataIC50:  761nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435043(CHEMBL2391296)
Affinity DataIC50:  761nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425314(CHEMBL2315877)
Affinity DataIC50:  850nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50270615(CHEMBL521286 | N-(4-chloro-3-(5-methylbenzo[d]oxaz...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435049(CHEMBL2391287)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425319(CHEMBL2315860)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435053(CHEMBL2391288)
Affinity DataIC50:  4.85E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435052(CHEMBL2391290)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426969(CHEMBL2325081)
Affinity DataIC50:  6.75E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435052(CHEMBL2391290)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435050(CHEMBL2391292)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435051(CHEMBL2391291)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435050(CHEMBL2391292)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435051(CHEMBL2391291)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PGDS in human 1483 cells assessed as eicosanoid level incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of 5-LOX in human 1483 cells assessed as eicosanoid level incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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