Compile Data Set for Download or QSAR
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Found 9 Enz. Inhib. hit(s) with all data for entry = 50042667
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50231755(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
Affinity DataIC50:  20nMAssay Description:Modulation of mGluR5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429062(CHEMBL2335279)
Affinity DataIC50:  410nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429061(CHEMBL2335285)
Affinity DataIC50:  430nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429059(CHEMBL2335295)
Affinity DataIC50:  750nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429060(CHEMBL2335291)
Affinity DataIC50:  940nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429060(CHEMBL2335291)
Affinity DataIC50:  2.03E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429059(CHEMBL2335295)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429062(CHEMBL2335279)
Affinity DataIC50:  6.17E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429061(CHEMBL2335285)
Affinity DataIC50:  6.53E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed