Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50042836
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431891(CHEMBL2347651)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50:  6nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431890(CHEMBL2347656)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431889(CHEMBL2347653)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431892(CHEMBL2347652)
Affinity DataIC50:  40nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431888(CHEMBL2347654)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50330550(CHEMBL1277474 | N-(4-chlorophenyl)-2,7,7-trimethyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human Eg5 catalytic domain assessed as inhibition of microtubulin-induced ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50323769((4S)-4-(3-HYDROXYPHENYL)-7,7-DIMETHYL-2-THIOXO-2,3...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431887(CHEMBL2347798)
Affinity DataIC50:  350nMAssay Description:Inhibition of human His-tagged Eg5 (1 to 368 amino acid residues) basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  520nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431884(CHEMBL2347649)
Affinity DataIC50:  650nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human Eg5 catalytic domain basal ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Eg5 in human HCT116 cells assessed as inhibition of microtubule-induced ATPase activity after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50323768((S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAH...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50192334(CHEMBL426141 | adociasulfate-2)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50192334(CHEMBL426141 | adociasulfate-2)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431885(TERPENDOLE E)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431885(TERPENDOLE E)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human Eg5 assessed as inhibition of microtubule-induced ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50216502(4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tet...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed